Sentinel lymph node biopsy guideline concordance in melanoma: Analysis of the National Cancer Database.

Journal of Surgical Oncology
Jatin NarangLuke D Rothermel

Abstract

This study investigated the impact of treating facility type on guideline-concordant sentinel lymph node biopsy (SLNB) management in T1a* (defined as a Breslow depth <0.76 mm without ulceration or mitoses) and T2/T3 melanoma. This was a retrospective cohort study utilizing the National Cancer Database from 2012 to 2016. Our cohort included 109,432 patients. For T1a* melanomas, 85% of patients received guideline-concordant SLNB management at community and academic facilities versus 75% of patients at integrated network facilities (p < .001). Over 83% of patients with T2/T3 melanoma treated at an academic facility received guideline-concordant SLNB management versus 77% treated at a community facility (p < .001). Adjusting for demographic and clinical factors, integrated (adjusted odds ratio, aOR = 0.54), and comprehensive community (aOR = 0.74) facilities were less likely to provide guideline-concordant SLNB management in patients with T1a* melanoma compared to academic facilities. Community facilities (aOR = 0.72) were less likely to provide guideline-concordant SLNB management in patients with T2/T3 melanoma compared to academic facilities. Academic facilities provide the highest rate of guideline-concordant sentinel lymph nod...Continue Reading

References

Nov 15, 2000·American Journal of Public Health·D B MukamelD L Weimer
Nov 8, 2003·Surgery·Doreen M AgneseMichael J Walker
Mar 22, 2005·Medical Care·Amber E BarnatoAmitabh Chandra
Sep 29, 2006·The New England Journal of Medicine·Donald L MortonUNKNOWN MSLT Group
Feb 23, 2008·The Annals of Thoracic Surgery·Robert A MeguidStephen C Yang
Mar 28, 2008·Journal of the National Cancer Institute·Amy Y ChenElizabeth Ward
Mar 11, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Karl Y BilimoriaJulie R Lange
Jul 29, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Karl Y BilimoriaClifford Y Ko
Oct 15, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Karl Y BilimoriaClifford Y Ko
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles M BalchVernon K Sondak
Apr 6, 2011·Journal of the American College of Surgeons·Jonathan S ZagerStephen R Grobmyer
Jul 11, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sandra L WongUNKNOWN Society of Surgical Oncology
Feb 6, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kathryn J MartiresJeremy S Bordeaux
Feb 14, 2014·The New England Journal of Medicine·Donald L MortonUNKNOWN MSLT Group
Jul 27, 2014·Annals of Surgical Oncology·Swapnil D KachareTimothy L Fitzgerald
Nov 13, 2014·Annals of Surgical Oncology·S RiberoP Quaglino
Oct 17, 2015·Annals of Surgical Oncology·David E GyorkiMichael A Henderson
Dec 15, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Mary E CharltonJohn W Cromwell
Jul 18, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J A MoodyJ T Hardwicke
Aug 17, 2016·Annals of Surgical Oncology·Danielle M BelloDale Han
Feb 6, 2017·International Journal of Health Services : Planning, Administration, Evaluation·Roosa Sofia TikkanenKaren E Lasser
Dec 13, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sandra L WongGary H Lyman
Jun 1, 2018·Annals of Surgical Oncology·Jeffrey E Gershenwald, Richard A Scolyer
Dec 7, 2018·Journal of Surgical Oncology·Ravinder KangSandra L Wong
Sep 20, 2019·Annals of Surgical Oncology·Danielle M Bello, Mark B Faries
Jan 9, 2020·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Apr 12, 2020·Journal of the American Academy of Dermatology·Raghav TripathiJeremy S Bordeaux
Jun 10, 2020·Annals of Surgical Oncology·Yinin HuMary S Brady

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