Sentinel lymph node biopsy in breast cancer: a technical and clinical appraisal

Nuclear Medicine Communications
Gianpiero MancaDuccio Volterrani

Abstract

Breast cancer is the most common type of cancer diagnosed in women worldwide. Regional lymph node status is one of the strongest predictors of long-term prognosis in primary breast cancer. Sentinel lymph node biopsy (SLNB) has replaced axillary lymph node dissection as the standard surgical procedure for staging clinically tumor-free regional nodes in patients with early-stage breast cancer. SLNB staging considerably reduces surgical morbidity in terms of shoulder dysfunction and lymphedema, without affecting diagnostic accuracy and prognostic information. Clinicians should not recommend axillary lymph node dissection for women with early-stage breast cancer who have tumor-free findings on SLNB because there is no advantage in terms of overall survival and disease-free survival. Starting from the early 1990s, SLNB has increasingly been used in breast cancer management, but its role is still debated under many clinical circumstances. Moreover, there is still a lack of standardization of the basic technical details of the procedure that is likely to be responsible for the variability found in the false-negative rate of the procedure (5.5-16.7%). In this article, we report the aspects of SLNB that are well established, those that ...Continue Reading

References

Mar 14, 2001·Journal of the American College of Surgeons·P J TanisB B Kroon
Apr 21, 2001·Annals of Surgical Oncology·K M McMastersM J Edwards
Jul 31, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·G CserniUNKNOWN European Working Group for Breast Screening Pathology
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology
Oct 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Gianpiero MancaGiuliano Mariani
Jan 6, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nathan J CoombsOwen A Ung
Jan 15, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Jean-Cyril BourreJean-Philippe Vuillez
Jan 21, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A J SpillaneR F Uren
Feb 3, 2009·Journal of the American College of Surgeons·Liang-Chih LiuStanley P Leong
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Apr 1, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Thomas WendlerAndreas K Buck
Apr 17, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Lenka VermeerenMichiel W M van den Brekel
Jan 21, 2011·The New England Journal of Medicine·Donald L WeaverNorman Wolmark
Feb 10, 2011·JAMA : the Journal of the American Medical Association·Armando E GiulianoMonica Morrow
Feb 16, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Elif HindiéMarc Espié
Mar 18, 2011·Maturitas·Rebecca Wiatrek, Laura Kruper
Jun 29, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A GoldhirschUNKNOWN Panel members
Aug 1, 2012·Annals of Surgical Oncology·Abigail S CaudleElizabeth A Mittendorf
Jan 2, 2013·Nuclear Medicine Communications·Thomas WagnerShaunak Navalkissoor
Mar 16, 2013·The Lancet Oncology·Viviana GalimbertiUNKNOWN International Breast Cancer Study Group Trial 23-01 investigators
Jun 12, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Christina BluemelMarion Kiechle
Oct 3, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Francesco GiammarileSergi Vidal Sicart
Oct 9, 2013·JAMA : the Journal of the American Medical Association·Judy C BougheyUNKNOWN Alliance for Clinical Trials in Oncology
Mar 26, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology Clinical Practice
Jul 25, 2014·Nuklearmedizin. Nuclear Medicine·M FreesmeyerA Darr
May 6, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A S CoatesUNKNOWN Panel Members
May 10, 2015·Journal of Nuclear Medicine Technology·Devaki Shilpa SurasiPradeep Bhambhvani
May 29, 2015·Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists·Tomasz NowikiewiczWojciech Zegarski

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Methods Mentioned

BETA
imaging techniques
dissection
biopsy
nucleic acid amplification

Software Mentioned

fhSPECT

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