Sentinel lymph node biopsy using computed tomographic lymphography in patients with early tongue cancer

Acta Oto-laryngologica
Kohei HondaKazuo Ishikawa

Abstract

Because computed tomography (CT) lymphography provides preoperative images of anatomic relationships between a tumor, its associated lymph vessels, and the sentinel lymph node (SLN), it may aid in directing the SLN biopsy for management of early tongue cancer. SLN biopsy using a radioisotope (RI) generally has been performed in head and neck cancer. However, this method can be performed only at institutions that are licenced for its use. In this study, we evaluated the utility of performing SLN biopsy in patients with early tongue cancer using the newly developed technique of CT lymphography. Enrolled in this study were 31 patients with T1N0 or T2N0 tongue cancer. CT images were obtained before and after injection of iopamidol into the peritumoral region and the SLN was identified as the first enhanced lymph node. SLN biopsy was performed using CT lymphographic guidance combined with blue dye injection. The SLN was detected by CT lymphography in 28 cases (90.3%). By intraoperative frozen section examination, metastases to SLNs were found in 4 (14.3%) (T1N0, 1 patient; T2N0, 3 patients) of the 28 patients. Of these four, SLN micrometastases were found in one patient.

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Citations

Jan 4, 2017·Dento Maxillo Facial Radiology·Shalva R GvetadzeJian Sun
Jun 28, 2019·JAMA Otolaryngology-- Head & Neck Surgery·Remco de BreeBart de Keizer
Sep 14, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Yue YangHaitao Wu
Nov 14, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Satomi SugiyamaKenji Mitsudo
Feb 27, 2021·Frontiers in Oncology·Daphne A J J DriessenJohannes H A M Kaanders

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Methods Mentioned

BETA
imaging techniques
dissection
biopsy
biopsies

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