Abstract
Although sentinel lymph node (SLN) identification is widespread used in melanoma and breast cancer some concerns exist in other malignancies, such gynaecologic cancers, and this staging method has not been adopted in many centers due to lack or large validation studies. To evaluate the applicability and results of SLN technique in gynaecological malignancies referred to our institution. We studied 155 patients with different malignancies (70 vulvar, 50 cervical and 35 endometrial cancers). The day before surgery a lymphoscintigraphy was performed by injecting 111 MBq of (99m)Tc-nanocolloid in several ways depending on the type of cancer studied. Intraoperative detection of the SLN was always performed by using a hand-held gammaprobe and, in 100 cases with the aid of blue dye injection (70 vulvar and 30 in cervical cancer) few minutes before surgical intervention. Pathological study of SLN was performed in all cases. Lymphadenectomy was done in all cervix and endometrial cancer patients and in the first 35 vulvar cancer patients. Pre-surgical lymphoscintigraphy demonstrated one, at least, SLN in 97% of vulvar cancer patients, 92% in the cervical malignancy and 64% in the endometrial cancer patients. During surgery, SLN was harve...Continue Reading
References
Nov 1, 1994·Cancer·D PaladiniJ M Monaghan
Dec 17, 2003·Gynecologic Oncology·Marie PlanteMichel Roy
Feb 10, 2004·Gynecologic Oncology·Hitoshi NiikuraNobuo Yaegashi
Mar 3, 2004·Journal of Surgical Oncology·Marco GipponiFerdinando Cafiero
May 7, 2004·Current Opinion in Obstetrics & Gynecology·Aureli Torné, Luis M Puig-Tintoré
Sep 3, 2004·American Journal of Obstetrics and Gynecology·Francesco RaspagliesiEugenio Solima
Dec 31, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Marco MaccauroEmilio Bombardieri
May 24, 2005·European Journal of Nuclear Medicine and Molecular Imaging·I RocaJ Xercavins
Jun 18, 2005·Gynecologic Oncology·Lukas RobMartin Hrehorcak
Aug 25, 2005·Journal of Surgical Oncology·Pieter J TanisOmgo E Nieweg
Apr 8, 2006·Gynecologic Oncology·Simone MarnitzUNKNOWN German Association of Gynecologic Oncologists (AGO)
May 10, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·H Y WangS Q Fu
May 10, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·D WydraJ Emerich
Jun 20, 2006·Gynecologic Oncology·Ion PopaBernard Têtu
Sep 29, 2006·CA: a Cancer Journal for Clinicians·Steven L ChenAnton J Bilchik
Jun 8, 2007·Gynecologic Oncology·Niraj N Mahajan
Jul 13, 2007·Cancer·Jan HauspyAllan Covens
Jul 14, 2007·Gynecologic Oncology·Jonas van de LandeRené H M Verheijen
Feb 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ate G J Van der ZeeWim J Sluiter
Mar 26, 2008·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Tara J SelmanKhalid Khan
Apr 2, 2008·Gynecologic Oncology·Pavel StrnadLukas Rob
May 22, 2008·World Journal of Surgical Oncology·Ali AyhanPolat Dursun
Aug 8, 2008·Gynecologic Oncology·A Nickles FaderL Cencia Rohan
Sep 23, 2008·Gynecologic Oncology·Monika HamplUNKNOWN German Multicenter Study Group
Dec 17, 2008·Gynecologic Oncology·Marcos BallesterEmile Daraï
Citations
Jun 18, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Silvia Rodríguez VillalbaJosé Manuel Cervera Grau
Oct 17, 2012·Revista española de medicina nuclear e imagen molecular·J M Cordero GarcíaA Soriano Castrejón
Jul 26, 2011·Revista española de medicina nuclear·S Vidal-SicartR A Valdés-Olmos
Nov 13, 2015·IEEE Transactions on Medical Imaging·Bernhard FuerstNassir Navab
Jun 28, 2014·The Cochrane Database of Systematic Reviews·Theresa A LawrieAngela Ralte
Oct 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Tessa A EnnikPeter T Grant
May 18, 2010·Current Opinion in Oncology·Zeina Al-Mansour, Claire Verschraegen
Mar 13, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Francesco GiammarileSergi Vidal Sicart
Dec 21, 2010·Expert Review of Anticancer Therapy·Valerio MaisGian Benedetto Melis
Jun 10, 2021·The Cochrane Database of Systematic Reviews·Hans NagarJo Morrison
Dec 6, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H JavanM Keshtgar