SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017)

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
M Martínez-GarciaM Gil-Gil

Abstract

Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy is the current standard of care for patients with newly diagnosed GB up to age 70. Recently, a new standard of care has been adopted for elderly patients (≥ 65 years) based on short course of RT and TMZ. Several clinically relevant molecular markers that assist in diagnosis and prognosis have recently been identified. The treatment for recurrent GB is not well defined, and decision-making is usually based on prior strategies as well as several clinical and radiological factors. The presence of neurologic deficits and seizures can significantly impact quality of life.

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Citations

Jan 23, 2020·Journal of the Royal Society, Interface·Inmaculada C SorribesHarsh V Jain
Jul 19, 2020·Journal of Biomedical Materials Research. Part a·Bowen TanJinfeng Liao
Dec 20, 2018·International Journal of Molecular Sciences·Thomas C ChenAxel H Schönthal
Oct 12, 2018·Scientific Reports·Jing TangYang Zhang
Dec 12, 2019·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·O A AbdullayevA L Krivoshapkin
Jun 20, 2020·Acta neurochirurgica·Juan Delgado-FernándezRafael García de Sola
Jan 25, 2018·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·A Santaballa, R Vera
Jan 4, 2021·Clinical Neurology and Neurosurgery·Mayla Santana CorreiaWellingson Silva Paiva
Dec 11, 2019·World Neurosurgery·Courtney L MonroeN Scott Litofsky
Nov 30, 2020·Drug Discovery Today·Rebecca KassubekHeiko G Niessen
May 7, 2021·Bioscience Reports·Ding ZhouXiuping Zhou
Jul 16, 2020·Current Drug Metabolism·Elmira MohtashamiAmir R Afshari
Apr 6, 2020·Stereotactic and Functional Neurosurgery·Gokhan YaprakNecati Tatarlı

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Methods Mentioned

BETA
total resection
biopsy
PCR

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