Separating local from global effects in neural pair correlograms

Neuroreport
Jos J Eggermont, G M Smith

Abstract

Cross-correlograms between spike trains of simultaneously recorded units in cortex show peaks that range in width from a few milliseconds to tens of milliseconds regardless of the distance between the units. The peak width reflects the degree of synchronization between the firings resulting from local connectivity and global synchronization. The local connectivity part may be hidden in the much stronger and broader correlations due to diffuse global synchronizing forces. This study proposes an estimator for such global synchronizing effects upon unit-pair correlations based on local field potentials (LFPs). It appears that the relative importance of the global component in the unit-pair correlograms as predicted by LFPs is largest in spontaneous activity and for units recorded on distant electrodes.

Citations

May 14, 1998·Neuroscience and Biobehavioral Reviews·J J Eggermont
Nov 17, 1999·The European Journal of Neuroscience·M Brosch, C E Schreiner
Mar 9, 2010·PloS One·Craig A Atencio, Christoph E Schreiner
Jun 20, 2006·Nature Neuroscience·Arnaud J NoreñaJos J Eggermont
Jul 5, 2008·The European Journal of Neuroscience·Boris Gourévitch, Jos J Eggermont
Dec 29, 2004·Vision Research·David J Warren, Richard A Normann
Sep 3, 2004·Journal of Neurophysiology·Masahiko Tomita, Jos J Eggermont
Jan 5, 2007·Journal of Neurophysiology·Boris Gourévitch, Jos J Eggermont

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