Separating the FN400 and N400 potentials across recognition memory experiments

Brain Research
Paweł StróżakTim Curran

Abstract

There is a growing debate as to whether frontally distributed FN400 potentials reflect familiarity-based recognition or are functionally identical to centro-parietal N400 reflecting semantic processing. We conducted two experiments in which event-related potentials (ERPs) associated with semantic priming and recognition were recorded, either when priming was embedded within a recognition test (Experiment 1), or when these two phases were separated (Experiment 2). In Experiment 1, we observed 300-500 ms differences between primed and unprimed old words as well as differences between old and new primed words, but these two effects did not differ topographically and both showed midline central maxima. In Experiment 2, the N400 for priming was recorded exclusively during encoding and again showed a midline central distribution. The ERP component of recognition was only found for unrelated words (not primed previously during encoding), and also showed a midline central maximum, but, in addition, was present in the left frontal area of the scalp. Conversely, the priming effect was absent in the left frontal cluster. This pattern of results indicate that FN400 and N400 potentials share similar neural generators; but when priming and r...Continue Reading

References

Sep 1, 1993·Electroencephalography and Clinical Neurophysiology·D M Tucker
Jul 13, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M JunghöferC Braun
Dec 6, 2000·Memory & Cognition·T Curran
Apr 17, 2001·The Behavioral and Brain Sciences·J P Aggleton, M W Brown
Aug 17, 2001·Journal of Cognitive Neuroscience·A D WagnerD L Schacter
Jan 20, 2004·Neuropsychologia·Astrid M Schloerscheidt, Michael D Rugg
Jan 12, 2005·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Douglas L NelsonThomas A Schreiber
Jan 31, 2006·Biological Psychology·Edward L Wilding
May 4, 2007·Trends in Cognitive Sciences·Ken A PallerStephan G Boehm
May 8, 2007·Trends in Cognitive Sciences·Michael D Rugg, Tim Curran
Jul 20, 2007·Experimental Brain Research·Ingo G MeisterBabak Boroojerdi
Oct 1, 2008·Journal of Cognitive Neuroscience·Ullrich K H Ecker, Hubert D Zimmer
Mar 31, 2010·Journal of Cognitive Neuroscience·Tim Curran, Jeanne Doyle
Sep 3, 2010·Annual Review of Psychology·Marta Kutas, Kara D Federmeier
Aug 2, 2012·NeuroImage·Emma K BridgerAxel Mecklinger
Jan 1, 1994·Journal of Cognitive Neuroscience·M BeemanM B Lindsay

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Citations

Jun 23, 2016·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Olivier BoucherJoseph L Jacobson
Jul 28, 2016·Psychophysiology·Paweł StróżakTim Curran
Apr 8, 2017·Journal of Cognitive Neuroscience·Regine Bader, Axel Mecklinger
Sep 13, 2020·Autism Research : Official Journal of the International Society for Autism Research·Pierre DesaunayBérengère Guillery-Girard
Dec 30, 2016·Journal of Cognitive Neuroscience·Qiong ZhangJohn R Anderson
Nov 27, 2020·Psychophysiology·Katie HoemannKaren S Quigley
Dec 29, 2020·Brain and Cognition·Paweł StróżakMarcin Wojtasiński
Jun 17, 2020·Neuropsychologia·Axel Mecklinger, Regine Bader
Jan 8, 2021·Cognitive, Affective & Behavioral Neuroscience·Jason D OzubkoRichard J Addante
Mar 29, 2021·Biological Psychology·Baoxi WangLing Xiang
Oct 12, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·P Andrew Leynes, Brittany A Mok

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