Separation and measurement of flame-formed high molecular weight polycyclic aromatic hydrocarbons by size-exclusion chromatography and laser desorption/ionization time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry : RCM
B ApicellaA Ciajolo

Abstract

The partial contribution of polycyclic aromatic hydrocarbons (PAH), capable of being detected by gas chromatography (GC-PAH), both to the total mass of the extractable organic fraction of flame-formed carbon particulates and to its UV-visible absorption and fluorescence spectra, has been determined by previous work. This contribution indicates the presence of PAH of molecular weight (MW) greater than 400 Da not accessible to conventional analysis. The detection of species in this higher MW range is important for both their potential toxicology and their possible role in soot formation. In the present work extracts of soots have been analyzed by linear mode laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) to extend the MW range that can be analyzed beyond the GC-PAH. The results have been compared with both analysis by reflector mode LDI-TOF-MS and the MW evaluation obtained by SEC analysis, as the shortcomings and advantages of both techniques appear to be complementary. Matching the results from the two techniques could give interesting insights in the molecular mass range between GC-PAH and the first soot particles (of mass > 2000 Da). Mass spectra in this molecular mass range have been obtained with ...Continue Reading

References

Jan 1, 1994·Annual Review of Public Health·D W Dockery, C A Pope
Aug 3, 2002·Environmental Health Perspectives·Günter Oberdörster, Mark J Utell
Apr 30, 2003·Chemosphere·L A SgroA D'Alessio

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Citations

Mar 8, 2007·Rapid Communications in Mass Spectrometry : RCM·Joachim HappoldManfred Aigner
Nov 15, 2006·Journal of Mass Spectrometry : JMS
Oct 12, 2019·Scientific Reports·Carmela RussoAnna Ciajolo

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