Separation of 2-Chloropyridine/3-Chloropyridine by Nonporous Adaptive Crystals of Pillararenes with Different Substituents and Cavity Sizes

Journal of the American Chemical Society
Xinru ShengFeihe Huang

Abstract

Two monochloropyridine isomers, 2-chloropyridine (2-CP) and 3-chloropyridine (3-CP), are in need of a more effective separation method besides rectification. Herein we offer a facile and energy-saving adsorptive separation way using nonporous adaptive crystals of perethylated pillar[5]arene (EtP5), perethylated pillar[6]arene (EtP6), perbromoethylated pillar[5]arene (BrP5) and perbromoethylated pillar[6]arene (BrP6), which possess different cavity sizes and substituents and have never been employed in the separation of single-substituted heterocyclic aromatic compounds. BrP6 crystals show a marked preference for 2-CP in the equimolar mixture of 2-CP and 3-CP, affording it with 96.4% purity. Single crystal diffraction experiments demonstrate that BrP6 has stronger host-guest interactions with 2-CP than 3-CP. The cycling experiments demonstrate that BrP6 crystals can be used at least five times without losing their adsorption selectivity or capacity.

References

Mar 25, 2008·Journal of the American Chemical Society·Tomoki OgoshiYoshiaki Nakamoto
Nov 20, 2009·Angewandte Chemie·Derong CaoHerbert Meier
May 26, 2012·Chemical Communications : Chem Comm·Yong YaoFeihe Huang
Dec 22, 2012·Journal of the American Chemical Society·Hui LiYing-Wei Yang
Aug 10, 2013·ACS Nano·Huacheng ZhangYanli Zhao
Mar 29, 2014·Angewandte Chemie·J E WarrenM J Rosseinsky
Jul 3, 2015·Angewandte Chemie·Tomoki OgoshiTada-aki Yamagishi
Jun 24, 2016·Chemical Reviews·Tomoki OgoshiYoshiaki Nakamoto
Feb 13, 2018·Journal of the American Chemical Society·Kecheng JieFeihe Huang
May 15, 2018·Journal of the American Chemical Society·Kecheng JieAndrew I Cooper
Jun 6, 2018·Chemical Society Reviews·Huacheng ZhangYanli Zhao
Jul 17, 2018·Accounts of Chemical Research·Kecheng JieFeihe Huang
Sep 21, 2018·Chemical Society Reviews·Angelo KirchonHong-Cai Zhou
Apr 24, 2019·Chemical Society Reviews·Xiaofan JiJonathan L Sessler
Jul 13, 2019·Journal of the American Chemical Society·Yujuan ZhouFeihe Huang
Jul 18, 2019·Journal of the American Chemical Society·Jia-Rui Wu, Ying-Wei Yang

❮ Previous
Next ❯

Citations

Jul 8, 2020·Angewandte Chemie·Jia-Rui Wu, Ying-Wei Yang
Aug 26, 2020·Angewandte Chemie·Chunju LiLei Cui
Feb 17, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Fei LiJunqiu Liu
Dec 18, 2020·Accounts of Chemical Research·Gengwu ZhangNiveen M Khashab
Nov 9, 2021·Journal of the American Chemical Society·Dan LuoXiaodong Chi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.