Separation of micro and sub-micro diamagnetic particles in dual ferrofluid streams based on negative magnetophoresis.

Electrophoresis
Chun-Dong XueKai-Rong Qin

Abstract

In the present study, we numerically demonstrate an approach for separation of micro and sub-micro diamagnetic particles in dual ferrofluid streams based on negative magnetophoresis. The dual streams are constructed by an intermediate sheath flow, after which the negative magnetophoretic force induced by an array of permanent magnets dominates the separation of diamagnetic particles. A simple and efficient numerical model is developed to calculate the motions of particles under the action of magnetic field and flow field. Effects of the average flow velocity, the ratio of sheath fluid flow to sample fluid flow, the number of the magnet pair as well as the position of magnet pair are investigated. The optimal parametric condition for complete separation is obtained through the parametric analysis, and the separation principle is further elucidated by the force analysis. The separation of smaller micro and sub-micro diamagnetic particles is finally demonstrated. This study provides an insight into the negative magnetophoretic phenomenon and guides the fabrication of feasible, low-cost diagnostic devices for sub-micro particle separation.

References

Dec 24, 2005·Lab on a Chip·Nicole Pamme
Feb 21, 2006·Biomechanics and Modeling in Mechanobiology·J H-C Wang, B P Thampatty
Apr 30, 2009·Annual Review of Biomedical Engineering·Deok-Ho KimYu Sun
Feb 25, 2010·Chemical Society Reviews·Andreas Lenshof, Thomas Laurell
Jun 5, 2012·Biomicrofluidics·Litao LiangXiangchun Xuan
Oct 9, 2014·Annual Review of Physiology·Stella Kourembanas
May 18, 2016·Biomicrofluidics·Ran Zhou, Cheng Wang
Jul 21, 2016·Small·Vasudha MurlidharSunitha Nagrath
Jul 1, 2017·Advanced Functional Materials·Wujun ZhaoLeidong Mao
Aug 16, 2017·Lab on a Chip·Wujun ZhaoLeidong Mao
Nov 21, 2017·Biomicrofluidics·Qi ChenXiangchun Xuan
Jan 18, 2018·Lab on a Chip·Dan YuanWeihua Li
Mar 2, 2018·Analytical Chemistry·Xinjie ZhangZhonghua Ni
Jun 12, 2018·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Fadi AlnaimatSaud Khashan
Jul 10, 2018·Biomicrofluidics·Ahmed MunazNam-Trung Nguyen
Jul 13, 2018·Analytical Chemistry·Nan XiangZhonghua Ni
Mar 20, 2019·Nanoscale·Xiaoming ChenHongyuan Jiang
Jun 25, 2019·Microsystems & Nanoengineering·Mengxi WuTony Jun Huang

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