Separation of seventeen 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and dibenzofurans and 12 dioxin-like polychlorinated biphenyls by comprehensive two-dimensional gas chromatography with electron-capture detection

Journal of Chromatography. a
Peter KorytárU A Brinkman

Abstract

Comprehensive two-dimensional gas chromatography (GC x GC) with electron-capture detection (ECD) has been optimized for the separation of seventeen 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and dibenzofurans and 12 dioxin-like polychlorinated biphenyls, with emphasis on the selection of the first- and second-dimension, commercially available, columns. When eight second-dimension columns were subsequently combined with a 100% methylpolysiloxane stationary phase (DB-1) in the first dimension to create orthogonal conditions, a complete separation of all congeners with different TEF values was obtained with two column combinations, DB-1 x VF-23 and DB-1 x LC-50. When other types of first-dimension columns were used (and orthogonality was partly sacrificed), a DB-XLB column combined with 007-65HT, VF-23 and LC-50 was found to provide a complete separation of all 29 priority congeners. Next, the potential of these three column combinations for real-life analysis was preliminarily studied. With a spiked and fractionated milk extract, DB-XLB x LC-50 was found to be the most powerful column combination, because of the good separation of the 29 priority congeners from each other as well as from the matrix constituents. Quanti...Continue Reading

References

Jul 24, 2002·Journal of Chromatography. a·Peter KorytárU A Th Brinkman
Jul 25, 2003·Journal of Chromatography. a·Jens DallügeUdo A Th Brinkman
Dec 3, 2003·Journal of Chromatography. a·Mikael HarjuPeter Haglund

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Citations

Feb 1, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Philip J MarriottRuby C Y Ong
Feb 8, 2008·Analytical and Bioanalytical Chemistry·Peter HaglundJacob de Boer
Jan 22, 2008·Journal of Chromatography. a·M AdahchourU A Th Brinkman
Jan 16, 2007·Chemosphere·Marc BassompierreSøren Balling Engelsen
Aug 13, 2009·Mass Spectrometry Reviews·Eric J Reiner
Sep 1, 2005·Journal of Chromatography. a·Mohamed AdahchourUdo A Th Brinkman
Apr 23, 2005·Journal of Chromatography. a·Jean-François FocantEdwin De Pauw
Jun 13, 2006·Journal of Chromatography. a·Luisa R BordajandiMaría José González
Jul 22, 2015·Environmental Science and Pollution Research International·Shunji HashimotoYasuyuki Shibata
Sep 15, 2006·Journal of Separation Science·Carin von MühlenPhilip J Marriott
Oct 18, 2008·Journal of Separation Science·Weeraya KhummuengPhilip J Marriott
Sep 20, 2008·Environmental Science & Technology·Ewa SkoczyńskaJacob De Boer
Jun 15, 2005·Analytical Chemistry·Carolyn J Koester, Amal Moulik

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