Separation of thiazide diuretics and antihypertensive drugs by thin-layer chromatography

Journal of Chromatography
S J Stohs, G A Scratchley

Abstract

A procedure is reported for the thin-layer chromatographic (TLC) separation and identification of thiazide diuretics and other antihypertensive drugs. Several new solvent systems and a variety of possible detection reagents were examined. Twenty thiazides used routinely in therapy were successfully separated and identified. Use of the TLC systems and combinations of the detecting methods described should be useful for the identification of these drugs in biological fluids and in various dosage forms.

Citations

Nov 1, 1986·Biopharmaceutics & Drug Disposition·P G Welling
Apr 10, 1987·Journal of Chromatography·R O FullinfawR F Moulds

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.