Sepsis after elective surgery - incidence, aetiology and outcome

Acta Anaesthesiologica Scandinavica
E VesteinsdottirS Karason

Abstract

Sepsis requiring admission to intensive care (ICU) is a rare complication of elective surgery, but associated with high morbidity and mortality. The aim of this study was to describe the incidence and outcome of sepsis following elective surgery. This was a retrospective, observational study where all admissions to Icelandic ICUs during calendar years 2006, 2008, 2010, 2012, 2014 and 2016 were screened, identifing patients with sepsis following elective surgery (ACCP/SCCM criteria). The number of elective operations performed at the largest center (Landspitali) during the study years was collected. Descriptive statistics were used to assess the incidence and outcome of patients with sepsis after elective surgery. During the study years, 88 patients were admitted to Icelandic ICUs with sepsis following elective surgery. Of those, 80 were operated at Landspitali, where the incidence of sepsis was 0.19% per elective procedure, highest following pancreaticoduodenectomies (14%, CI 6-25) and esophagectomies (13%, CI 4-27), but the greatest number of patients (30% (26/88)) developed sepsis after a colorectal procedure. The most common infection sources were the abdomen (65% (57/88)) and lungs/mediastinum (22% (19/88)), frequently poly...Continue Reading

References

Mar 2, 2002·The British Journal of Surgery·A Sitges-SerraJ J Sancho
Nov 25, 2003·BMJ : British Medical Journal·Peter McCullochUNKNOWN British Oesophago-Gastric Cancer Group
Jan 22, 2004·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S Harbarth, I Uckay
Oct 18, 2005·British Journal of Anaesthesia·D MokartC Martin
Jan 29, 2008·The Annals of Thoracic Surgery·Andrew C ChangJohn D Birkmeyer
Dec 19, 2008·Critical Care : the Official Journal of the Critical Care Forum·Jesús BlancoUNKNOWN Grupo de Estudios y Análisis en Cuidados Intensivos
Mar 5, 2009·The Journal of Thoracic and Cardiovascular Surgery·Cameron D WrightUNKNOWN Society of Thoracic Surgeons General Thoracic Surgery Database
Aug 22, 2009·Chest·Anand KumarUNKNOWN Cooperative Antimicrobial Therapy of Septic Shock Database Research Group
Jun 24, 2010·Annals of Surgery·Todd R VogelStephen F Lowry
Mar 5, 2011·Anesthesiology·Alparslan TuranLeif Saager
Apr 13, 2011·Acta Anaesthesiologica Scandinavica·E VesteinsdottirG H Sigurdsson
May 22, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Benjamin D ShoganKonstantin Umanskiy
Dec 26, 2013·Annals of Surgery·Bradley N ReamesJustin B Dimick
Feb 4, 2014·Infectious Disease Clinics of North America·Carol E ChenowethSanjay Saint
Jul 31, 2014·BMC Infectious Diseases·Jan De WaeleUNKNOWN EPIC II Investigators
Aug 30, 2014·The Journal of Surgical Research·Jesse D SammonQuoc-Dien Trinh
Mar 25, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Timothy E NewhookVictor M Zaydfudim
Jan 27, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasJack D Sobel
Oct 1, 2016·Intensive Care Medicine·UNKNOWN SepNet Critical Care Trials Group
Nov 7, 2016·The Lancet Infectious Diseases·Benedetta AllegranziUNKNOWN WHO Guidelines Development Group
Dec 30, 2016·The Journal of Surgical Research·Akshay SoodQuoc-Dien Trinh
Feb 22, 2017·Critical Care : the Official Journal of the Critical Care Forum·Lixin OuRinaldo Bellomo
Apr 26, 2017·Intensive Care Medicine·Brennan C KahanUNKNOWN International Surgical Outcomes Study (ISOS) group
Jul 12, 2017·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J ArendsA Weimann
Feb 18, 2018·British Journal of Anaesthesia·S H HowittS W Grant
Aug 19, 2018·Surgery·Nakul ValsangkarThomas J Birdas
Oct 4, 2018·The Journal of Surgical Research·Sowmya NarayananVictor M Zaydfudim
Apr 23, 2020·Acta Anaesthesiologica Scandinavica·Susanne B WilhelmsLina De Geer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved