Sepsis-related mortality in China: a descriptive analysis

Intensive Care Medicine
Li WengChina Critical Care Clinical Trials Group (CCCCTG)

Abstract

A population-level description and analysis of sepsis-related mortality in China is key to the planning and assessment of interventional strategies. Retrospective analysis of multiple cause of death (MCOD) recorded in the population-based national mortality surveillance system (NMSS) of China. All sepsis-related deaths occurring in 605 disease surveillance points (DSPs) covering 323.8 million population across China were included in our study. Age-standardized mortality and national estimate of sepsis-related deaths were estimated using the census population in 2010 and 2015, respectively. In 2015, a total of 1,937,299 deaths occurring in any of the 605 DSPs and standardized sepsis-related mortality rate was 66.7 (95% confidence interval [CI] 66.4-67.0) deaths per 100,000 population. This produced a national estimate of 1,025,997 sepsis-related deaths. Sepsis-related mortality rates exhibited significant geographic variation. In multilevel analysis, male sex (rate ratio [RR] 1.582, 95% CI 1.570-1.595), increasing age (RR 1.914 for 5-year group, 95% CI 1.910-1.917), and presence of comorbidity (RR 2.316, 95% CI 2.298-2.335) were independently associated with increased sepsis-related mortality. Higher disposable income (RR 0.717 ...Continue Reading

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Citations

Oct 5, 2018·Intensive Care Medicine·Armand Mekontso Dessap
Jul 4, 2019·Intensive Care Medicine·Morten Hylander MøllerManu Shankar-Hari
Mar 7, 2020·Critical Care : the Official Journal of the Critical Care Forum·Huaiwu HeUNKNOWN China-NCCQC group
Sep 2, 2020·Critical Care : the Official Journal of the Critical Care Forum·Li WengLiming Li
Feb 6, 2020·Annals of Intensive Care·Run DongUNKNOWN China Critical Care Clinical Trials Group (CCCCTG)
Oct 21, 2020·Critical Care : the Official Journal of the Critical Care Forum·Wenqiang JiangHongke Zeng
Jan 5, 2021·Frontiers in Medicine·Meiping WangUNKNOWN China Critical Care Sepsis Trial (CCCST) workgroup
Feb 23, 2021·Journal of Intensive Care Medicine·Fei PengYi Yang
Mar 1, 2021·Journal of Translational Medicine·Jing-Yuan XuYi Yang
Mar 9, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Hui LiYuncong Sun
Mar 19, 2021·Journal of Primary Care & Community Health·Suraphan CharoentanyarakKittisak Sawanyawisuth
May 8, 2021·BioMed Research International·Zhaojun LiuErzhen Chen
May 16, 2021·The Journal of International Medical Research·Li LiLina Zhang
Apr 6, 2021·Aging and Disease·Xin DingUNKNOWN Chinese Critical Ultrasound Study Group
Aug 6, 2021·The American Journal of Emergency Medicine·Romain JouffroyBenoît Vivien
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Oct 1, 2021·Experimental Lung Research·Shengsong ChenQingyuan Zhan
Oct 9, 2021·Journal of Intensive Care·Jason PhuaUNKNOWN Asian Critical Care Clinical Trials Group
Aug 14, 2021·Critical Care Medicine·Simon FinferAnders Perner
Nov 2, 2021·Frontiers in Public Health·Dong WangTongwen Sun

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