Septal pouch in the left atrium: a new anatomical entity with potential for embolic complications

JACC. Cardiovascular Interventions
Subramaniam C Krishnan, Miguel Salazar

Abstract

The purpose of this study was to develop a better understanding of the pathophysiology of the condition, we studied the patterns by which the septum primum (SP) and septum secundum (SS) fuse. A patent foramen ovale (PFO) is a communication across the interatrial septum between a nonadherent SP and SS and is considered to be a risk factor for serious clinical syndromes. We examined the interatrial septum in 94 randomly selected autopsied hearts, with a focus on the SP and SS and the patterns by which the 2 structures fuse. Of the 94 specimens that were suitable for analysis, 26 (27.66%) had a PFO. Of the remaining 68 hearts, complete fusion of the SP and SS along the entire zone of overlap was seen in 27 (28.7%) hearts. In the remaining 41 hearts (60.29%), a PFO was absent, but incomplete fusion of the SP and SS was seen. Of 41 hearts, 37 (90%) had a septal pouch that opened into the left atrial (LA) cavity. Four hearts (10%) had a pouch accessible from the right atrium. Hearts with left-sided pouches tended to be younger (50 +/- 18 years of age) than hearts where there was complete fusion (age 63 +/- 23 years) (p = 0.06). Our data suggest that when a foramen ovale closes spontaneously, the SP and SS fuse initially at the caudal...Continue Reading

References

Sep 15, 1992·Annals of Internal Medicine·M Di TullioS Homma
Feb 1, 1996·The Annals of Thoracic Surgery·J L Blackshear, J A Odell
Jun 27, 2002·Journal of the American College of Cardiology·Martin U BraunRuth H Strasser
Jan 8, 2003·Circulation·Bernhard Meier, James E Lock
Apr 1, 2003·Journal of Interventional Cardiology·Eustaquio OnoratoGian Paolo Anzola
Aug 16, 2005·American Journal of Obstetrics and Gynecology·Afshan HameedUri Elkayam
Nov 1, 2005·Journal of the American College of Cardiology·Hidehiko HaraRobert S Schwartz
May 27, 2006·European Heart Journal·Ole-A BreithardtMartin Borggrefe
Jun 5, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ole-A Breithardt

❮ Previous
Next ❯

Citations

Apr 4, 2013·Herzschrittmachertherapie & Elektrophysiologie·Thorsten HankeTimo Weimar
Jun 24, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Hiroshi KuwakiYutaka Otsuji
Jan 1, 2011·Multimedia Manual of Cardiothoracic Surgery : MMCTS·Sacha P Salzberg, Herman Tolboom
Dec 2, 2010·The International Journal of Cardiovascular Imaging·María MartínCésar Morís
Jul 12, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ole-A Breithardt, Gerhard Hindricks
Feb 18, 2016·Radiology·Kemal KaraOnur Sildiroglu
Feb 18, 2016·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Wiesława Klimek-PiotrowskaJakub Hołda
Oct 22, 2015·Expert Review of Cardiovascular Therapy·Jonathan M Wong, Mark Fisher
May 18, 2016·Nature Reviews. Disease Primers·Shunichi HommaMarco R Di Tullio
May 18, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Jonathan M WongMark Fisher
Dec 3, 2010·European Journal of Radiology·Omur BalliMusturay Karcaaltincaba
Sep 29, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Paul E CotterMark Belham
Apr 12, 2016·International Journal of Cardiology·Sourabh AggarwalVishal Gupta
Jan 5, 2014·Journal of Cardiovascular Electrophysiology·Heiko LehrmannReinhold Weber
Aug 5, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Frank E SilvestryUNKNOWN Society for Cardiac Angiography and Interventions
Dec 18, 2010·JACC. Cardiovascular Imaging·Swaminatha V GurudevanSubramaniam C Krishnan
Apr 9, 2015·Frontiers in Neurology·Jonathan M WongMark Fisher
May 14, 2016·Echocardiography·Mihai StrachinaruMarie-Dominique Gazagnes
Jul 9, 2016·International Journal of Cardiology·Mateusz K HołdaWiesława Klimek-Piotrowska
Jul 1, 2016·Acta Radiologica Open·Silanath TerpenningStacy M Rissing
Mar 16, 2013·Journal of Cardiovascular Medicine·Mihai StrachinaruEmmanuel Catez
Apr 25, 2018·Echocardiography·Deepa Kabirdas, Rajasekhar Nekkanti
Nov 23, 2017·Expert Review of Cardiovascular Therapy·Francesca SalghettiCarlo de Asmundis
Sep 5, 2013·Journal of Clinical Ultrasound : JCU·Keiko ShimamotoIchiro Inoue
Feb 16, 2012·Circulation. Arrhythmia and Electrophysiology·Siew Yen HoDamian Sanchez-Quintana
Oct 13, 2011·Echocardiography·Siddharth A WayangankarChittur Sivaram
Mar 27, 2018·The International Journal of Cardiovascular Imaging·Mateusz K HołdaWiesława Klimek-Piotrowska
Feb 2, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Luigi Di BiaseSubramaniam C Krishnan
Jul 24, 2020·Thrombosis Journal·Snehasis PradhanHans-Joachim Trappe
Dec 30, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Yasufumi KijimaJonathan M Tobis
Jan 2, 2021·BMJ Case Reports·Hiroshi KuwakiKeiji Ujino
Jan 5, 2021·Translational Stroke Research·Ruchi KapoorMark Fisher
Jan 15, 2021·Heart·Francesco Fulvio FaletraSiew Yen Ho
Mar 13, 2021·European Heart Journal Cardiovascular Imaging·Ariel CohenUNKNOWN chair of the 2018–2020 EACVI Scientific Documents Committee
Mar 11, 2021·Anatomy & Cell Biology·Prajakta Kishve, Rohini Motwani
Jul 16, 2019·Cardiology·Mohammad AbdelghaniRobbert J de Winter
Nov 16, 2021·Cardiology in the Young·Salvatore CaputoGuido Rocchi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Cardiomegaly

Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.

Related Papers

JACC. Cardiovascular Imaging
Aylin TugcuMarco R Di Tullio
AJR. American Journal of Roentgenology
Eric E WilliamsonJerome F Breen
AJR. American Journal of Roentgenology
Oliver K MohrsThomas Voigtlaender
© 2021 Meta ULC. All rights reserved