Septic arthritis caused by Nocardia asteroides in a renal transplant recipient

Transplantation Proceedings
S KahramanS Caglar

Abstract

Although articular complications are common following renal transplantation, septic arthritis is not frequent. Previous bacterial infection in an another site is a consistent finding and the knee is the most often affected joint. We present a 30-year-old female renal transplant recipient with recurrent pulmonary infiltrates preceding septic arthritis of her left knee. Cultures of the aspirated synovial fluid yielded a gram-positive, rod-shaped bacterium later identified as Nocardia asteroides. The patient was treated with oral trimethoprim-sulfamethoxazole without any side effect. Nocardia is a rare but serious cause of infection in renal transplant recipients but there is no well-known predisposing factor. Recently mycophenolate mofetil has been implicated as a factor associated with Nocardia infections. Prolonged courses of treatment with sulphonamides are recommended.

References

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Citations

May 29, 2010·Infection·I UçkayJ Schrenzel
Aug 10, 2011·Transplant Infectious Disease : an Official Journal of the Transplantation Society·X YuJ Chen
Jun 5, 2015·Journal of Clinical Microbiology·Elaine X L YongGenevieve L McKew
Oct 27, 2015·Medicine·Hélène ChaussadeOlivier Lortholary
Jan 1, 2014·International Scholarly Research Notices·Muhammad KhanSufyan Abdul Mujeeb

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