Septic cavernous sinus thrombosis: an unusual and fatal disease

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Huan-Wen ChenYee-Chun Chen

Abstract

Septic cavernous sinus thrombosis (CST) is a rare and fatal disease. Clinical presentations in the early stage are nonspecific, and the sensitivity of cranial axial computed tomography (CT) with thick section is low. This study analyzed the clinical manifestation and neuroimaging findings in patients with septic CST in a medical center in Taiwan. This retrospective case series included nine patients with septic CST who had typical symptoms and clinical course, evidence of infection, and imaging studies which demonstrated cavernous sinus lesion, and who were treated between 1995 and 2003 at National Taiwan University Hospital. Seven (77.8 %) patients were more than 50 years old. Five (55.6%) had diabetes, and three (33.3%) had hematologic diseases. All cases were associated with paranasal sinusitis. The most frequent initial symptom was headache (66.7%), followed by ophthalmic complaints (diplopia or ophthalmoplegia, 55.6%; blurred vision or blindness, 55.6%), and ptosis (44.4%). Initial cranial images failed to identify CTS in all patients. Subsequent magnetic resonance imaging (MRI) or coronal contrast-enhanced CT (CECT) with thin section confirmed the diagnosis. Fungi were the most common pathogens (55.6%). The inhospital cas...Continue Reading

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Citations

Mar 6, 2016·Journal of the Neurological Sciences·Ismail A Khatri, Mohammad Wasay
Apr 14, 2010·International Journal of Paediatric Dentistry·Suher Baker, Lia Parico
Dec 21, 2017·Vestnik otorinolaringologii·I E Berest, S N Mironets
Jan 16, 2015·American Journal of Rhinology & Allergy·Franklin LizéPhilippe Herman
Oct 16, 2018·Ophthalmic Plastic and Reconstructive Surgery·Sara V BransonR Patrick Yeatts
Dec 9, 2016·Neuro-ophthalmology·Dinushi Weerasinghe, Christian J Lueck
Jun 20, 2020·Emergency Radiology·Stephen M SmithAlexander T Kessler

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