Septicemia in patients with AIDS admitted to a university health system: a case series of eighty-three patients

Journal of the American Board of Family Medicine : JABFM
Richard I HaddyJulio A Ramirez

Abstract

Patients with AIDS incur higher rates of infection than the general population. However, little evidence exists to guide family physicians in selecting antibiotics for initial empiric therapy for suspected septicemia. We recorded the causative organisms of septicemia (defined here as bacteremia, fungemia, or both) in 83 patients with AIDS admitted to the teaching hospitals of the University of Louisville from 1996 to 2006. All patients fulfilled the requirements for a diagnosis of AIDS on the basis of the 1993 Centers for Disease Control criteria. In addition to the causative organism, demographic information, immunologic data, portal of entry, and mortality were collected. Only 53% of the patients presented with fever and the median leukocyte count was 4400 cells/mm(3). The most common organisms causing septicemia were, in decreasing order, methicillin-sensitive Staphylococcus aureus (MRSA; n = 21; 21.4%), Mycobacterium avium complex (n = 10; 10.2%), coagulase-negative staphylococci (n = 9; 9.2%) and Streptococcus pneumoniae (n = 9; 9.2%). Other pathogens included Escherichia coli, Pseudomonas aeruginosa, and MRSA. Polymicrobial septicemia was identified in 12 cases (14.5% of the episodes). The portals of entry of the organism...Continue Reading

Citations

Jul 23, 2013·PloS One·Rodrigo T AmancioFernando A Bozza
Jul 16, 2014·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·José Moreira

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