PMID: 6159574May 24, 1980Paper

Sequence analysis and in vitro maturation of five precursor 5S RNAs from Bacillus Q

Nucleic Acids Research
W J StiekemaR J Planta

Abstract

Bacillus Q, which is closely related to B. subtilis, contains at least six different precursors of 5S rRNA. The complete nucleotide sequences of four of these precursors, as well as the major part of the sequence of a fifth one, have been determined. They all contain the same 5'-terminal non-conserved segment which is to a large degree homologous with the corresponding segment of the B. subtilis p5S RNAs (Sogin, M.L., Pace, N.R., Rosenberg, M., Weissman, S.M. (1976) J. Biol. Chem. 251, 3480-3488). On the other hand the 3'-terminal non-conserved sequences of the various Bacillus Q precursors show considerable differences both in length and in nucleotide sequence, while there is also little or no homology with the 3'-terminal non-conserved sequence of the B. subtilis precursors. Bacillus Q p5S RNAs do not possess tetranucleotide repeats around the sites which are cleaved during maturation, as does B. subtilis p5S RNA. Like in B. subtilis, however, the cleavage sites are contained within a double-helical region of the precursor molecules. Crude RNAse M5 isolated from various Bacillus strains can maturate the Bacillus Q p5S RNAs with high efficiency. Despite considerable differences in primary structure between the precursors from ...Continue Reading

References

Jul 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·B MeyhackN R Pace
Jan 1, 1978·Annual Review of Biochemistry·S Adhya, M Gottesman
Nov 14, 1977·Molecular & General Genetics : MGG·H A RauéR J Planta
Aug 7, 1975·Nature·G E Fox, C R Woese
Nov 1, 1975·European Journal of Biochemistry·H A RauéR J Planta
Apr 25, 1973·Journal of Molecular Biology·N R PaceC W Radcliffe
Dec 1, 1969·European Journal of Biochemistry·G G Brownlee, F Sanger
Jan 1, 1969·Cold Spring Harbor Symposia on Quantitative Biology·R MonierF Varricchio
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Sep 1, 1965·Analytical Biochemistry·E G RichardsW B Gratzer
Dec 1, 1967·European Journal of Biochemistry·J Retèl, R J Planta

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Citations

Jan 22, 1982·Nucleic Acids Research·V A Erdmann
Oct 11, 1983·Nucleic Acids Research·K LoughneyJ E Dahlberg
Oct 10, 1980·Nucleic Acids Research·W J StiekemaR J Planta
Jan 10, 1981·Nucleic Acids Research·V A Erdmann
Dec 1, 1981·Microbiological Reviews·P Gegenheimer, D Apirion

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