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Sequence analysis of 0.5 Mb of the rabbit germline immunoglobulin heavy chain locus

Gene

Apr 17, 2004

Francesca RosJosef Platzer

Abstract

A bacterial artificial chromosome (BAC) library was created using partially digested rabbit chromosomal DNA. Four BAC clones spanning about 0.5 Mb of the rabbit immunoglobulin (Ig) heavy chain locus were isolated and sequenced. Three of the BAC clones were partially overlapping. Thirty-...read more

Mentioned in this Paper

Repetitive Region
Germ-Line Mutation
Immunoglobulin Activity
Exons
Genome
Molecular Diagnostics Gene Rearrangement (Lab Test)
Murine
Cosmids
SLC3A2 gene
Codon, Terminator
Paper Details
References
  • References20
  • Citations23
12
  • References20
  • Citations23
123

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B cell and antibody repertoire development in rabbits: the requirement of gut-associated lymphoid tissues

Developmental and Comparative ImmunologyAugust 16, 2005
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Sequence analysis of 0.5 Mb of the rabbit germline immunoglobulin heavy chain locus

Gene

Apr 17, 2004

Francesca RosJosef Platzer

PMID: 15087123

DOI: 10.1016/j.gene.2003.12.037

Abstract

A bacterial artificial chromosome (BAC) library was created using partially digested rabbit chromosomal DNA. Four BAC clones spanning about 0.5 Mb of the rabbit immunoglobulin (Ig) heavy chain locus were isolated and sequenced. Three of the BAC clones were partially overlapping. Thirty-...read more

Mentioned in this Paper

Repetitive Region
Germ-Line Mutation
Immunoglobulin Activity
Exons
Genome
Molecular Diagnostics Gene Rearrangement (Lab Test)
Murine
Cosmids
SLC3A2 gene
Codon, Terminator

Similar Papers Found In These Feeds

Artificial Chromosomes

Artificial chromosomes are genetically engineered chromosomes derived from the DNA of a species. Discover the latest research on artificial chromosomes here.

Exon Skipping

Exon skipping is a method of RNA splicing used when a mutation occurs in the genes of exons. It is regulated largely by the use of antisense oligonucleotides that mask the mutated gene and allow the cellular machinery to skip over it. Exon skipping is being investigated as a therapeutic option for some diseases. Here is the latest research on exon skipping.

Related Papers

Developmental and Comparative Immunology

B cell and antibody repertoire development in rabbits: the requirement of gut-associated lymphoid tissues

Developmental and Comparative ImmunologyAugust 16, 2005
Rose G MageKatherine L Knight
Paper Details
References
  • References20
  • Citations23
12
  • References20
  • Citations23
123
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