PMID: 6160476Feb 11, 1980Paper

Sequence and heterogeneity in the 5S RNA gene cluster of Drosophila melanogaster

Nucleic Acids Research
C Tschudi, V Pirrotta

Abstract

The sequence of the entire 5S RNA gene of Drosophila melanogaster was determined by sequencing collectively 23 copies contained in a cloned fragment of Drosophila DNA and by sequencing individually four subcloned gene copies. A repetitive heptamer (GCTG CCT) present in variable numbers immediately following the coding sequence, is responsible for the length heterogeneity in the spacer region. Some of the gene copies contain a nucleotide change in the coding region which results in a new site for the restriction enzyme Mn1 I. The variant 5S RNA produced by these gene copies has not been detected in vivo. Two other single nucleotide variations were identified in the spacer region.

References

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Citations

Jan 1, 1982·Molecular & General Genetics : MGG·R DeLottoP Schedl
Apr 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·K R Luehrsen, G E Fox
Feb 1, 1985·Journal of Biomolecular Structure & Dynamics·V B Zhurkin
Aug 11, 1982·Nucleic Acids Research·P B GoldsbroughG P Lomonossoff
Jan 11, 1983·Nucleic Acids Research·V A ErdmannR De Wachter
May 25, 1989·Nucleic Acids Research·R M RansohoffT W Nilsen
Jan 1, 1978·Nucleic Acids Research·V A Erdmann
Oct 10, 1981·Nucleic Acids Research·L DielsR De Wachter
Dec 11, 1981·Nucleic Acids Research·B K Kay, J G Gall
Jan 1, 1991·Genetica·C López-FernándezR Mezzannotte
Jan 1, 1985·Nucleic Acids Research·V A ErdmannR De Wachter
Jan 1, 1984·Nucleic Acids Research·V A ErdmannR De Wachter
Jan 1, 1992·DNA Sequence : the Journal of DNA Sequencing and Mapping·F C DavisL D Ingham

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