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Sequence co-evolution gives 3D contacts and structures of protein complexes

bioRxiv

May 6, 2014

Thomas A. HopfDebora S. Marks

Abstract

High-throughput experiments in bacteria and eukaryotic cells have identified tens of thousands of interactions between proteins. This genome-wide view of the protein interaction universe is coarse-grained, whilst fine-grained detail of macro-molecular interactions critically depends on ...read more

Mentioned in this Paper

Genome-Wide Association Study
Patterns
Genome
Three-dimensional
Complex (molecular entity)
Anatomical Space Structure
ATP synthase subunit 6
Protein-Protein Interaction
Binding (Molecular Function)
Structure
15
3
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Sequence co-evolution gives 3D contacts and structures of protein complexes

bioRxiv

May 6, 2014

Thomas A. HopfDebora S. Marks

PMID: 990004762

DOI: 10.1101/004762

Abstract

High-throughput experiments in bacteria and eukaryotic cells have identified tens of thousands of interactions between proteins. This genome-wide view of the protein interaction universe is coarse-grained, whilst fine-grained detail of macro-molecular interactions critically depends on ...read more

Mentioned in this Paper

Genome-Wide Association Study
Patterns
Genome
Three-dimensional
Complex (molecular entity)
Anatomical Space Structure
ATP synthase subunit 6
Protein-Protein Interaction
Binding (Molecular Function)
Structure
15
3

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