Sequence-selective osmium oxidation of DNA: efficient distinction between 5-methylcytosine and cytosine

Organic & Biomolecular Chemistry
Akimitsu OkamotoTaku Kamei

Abstract

5-Methylcytosine was distinguished from cytosine using the large difference of their osmium oxidation rates, and this reaction was applied to detection of the cytosine methylation status at a specific site of a long sequence using the formation of a bulge structure by hybridization with a guide DNA.

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Citations

Mar 23, 2011·Biochemistry·Akiko Nomura, Akimitsu Okamoto
Aug 27, 2009·The Journal of Physical Chemistry. B·Alyssa L SmithBruce H Robinson
Jun 23, 2011·Chemical Communications : Chem Comm·Akiko NomuraAkimitsu Okamoto
Dec 11, 2007·Nucleosides, Nucleotides & Nucleic Acids·Akimitsu Okamoto
Jul 21, 2011·Journal of Nucleic Acids·Kaori SugizakiAkimitsu Okamoto
May 12, 2017·Chemical Communications : Chem Comm·Taku MatsushitaAkimitsu Okamoto
Mar 30, 2017·Chemical Society Reviews·Yuqi ChenXiang Zhou
Aug 20, 2016·Lab on a Chip·Ryoji Kurita, Osamu Niwa
Aug 3, 2018·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Takuma SueokaAkimitsu Okamoto
Nov 28, 2007·Angewandte Chemie·Sébastian Bareyt, Thomas Carell
Oct 22, 2008·Organic & Biomolecular Chemistry·Akiko Nomura, Akimitsu Okamoto
Oct 3, 2008·Chemistry : a European Journal·Hisatsugu YamadaSei-Ichi Nishimoto
Jan 5, 2008·Organic & Biomolecular Chemistry·Tadashi Umemoto, Akimitsu Okamoto
Dec 17, 2008·Organic & Biomolecular Chemistry·Akimitsu Okamoto
Mar 13, 2014·The Analyst·Kenta Takanashi, Teru Kato
Mar 13, 2014·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Kenta Takanashi, Teru Kato
Jul 13, 2020·Histochemistry and Cell Biology·Takehiko Koji, Yasuaki Shibata
May 26, 2018·Chembiochem : a European Journal of Chemical Biology·Turja Kanti Debnath, Akimitsu Okamoto
Apr 19, 2011·Organic & Biomolecular Chemistry·Kaori SugizakiAkimitsu Okamoto
Dec 8, 2011·Current Protocols in Nucleic Acid Chemistry·Kazuki Tainaka, Akimitsu Okamoto
Oct 22, 2020·Chemical Communications : Chem Comm·Bapurao A BhogeIshu Saraogi
Feb 17, 2009·Bioconjugate Chemistry·Akiko NomuraAkimitsu Okamoto
Aug 14, 2012·Analytical Chemistry·Ryoji Kurita, Osamu Niwa
Aug 20, 2016·Bioconjugate Chemistry·Lyudmil Tserovski, Mark Helm

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