Sequences of the genes encoding argininosuccinate synthetase in Escherichia coli and Saccharomyces cerevisiae: comparison with methanogenic archaebacteria and mammals

Gene
F Van VlietN Glansdorff

Abstract

The nucleotide (nt) sequences of the genes encoding argininosuccinate synthetase from Escherichia coli K-12 (argG) and Saccharomyces cerevisiae (ARG1) were determined. The deduced amino-acid sequences were compared to each other and to their counterparts in two methanogens and in mammals. Three regions are highly conserved. Two of them appear to contain possible Walker-type nt-binding sites [Walker et al., EMBO J. 1 (1982) 945-951] and are therefore candidates for ATP-binding sites. The third region shows some similarity to a short portion of the N-proximal part of the PurA enzyme which catalyses an analogous reaction.

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Citations

Apr 24, 2003·European Journal of Biochemistry·Annie HussonAlain Lavoinne
Oct 25, 2012·PLoS Neglected Tropical Diseases·Ines Lakhal-NaouarRobert C Duncan
Jan 1, 1997·Human Mutation·H KakinokiT Saheki
Dec 1, 2004·EcoSal Plus·Daniel Charlier, Nicolas Glansdorff
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·M K Berlyn

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