journal cover

Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity

bioRxiv

Jul 3, 2014

C T WatsonF Breden

Abstract

Germline variation at immunoglobulin gene (IG) loci is critical for pathogen-mediated immunity, but establishing complete reference sequences in these regions is problematic because of segmental duplications and somatically rearranged source DNA. We sequenced BAC clones from the essenti...read more

Mentioned in this Paper

SLC3A2 gene
LECT1 gene
Hydatidiform Mole
Immunoglobulin G
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Proximal
Distal
Clone
Sequencing
8
1
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Chromosomal Duplication

Chromosomal duplication is a result of extra genetic material within the area of the chromosome. The duplication may have no effect or may be expressed in the phenotype of that individual. Some duplications are thought to be of evolutionary selection. Discover the latest research on chromosomal duplication here.

Copy Number Variation

Copy number variation refers to alterations in the number of gene copies or DNA sequences. It can be a duplication, amplification, or a deletion event. Here is the latest research.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

International Cancer Genome Consortium

The International Cancer Genome Consortium (ICGC) was founded with the goal of mapping the genome of 25,000 primary untreated cancers. The ICGC has also pushed for the global sharing of genomic data to facilitate cancer research. Find the latest research from the ICGC here.

McDonnell Genome Institute

The McDonnell Genome Institute (MGI) is a part of the Washington University School of Medicine in St. Louis. MGI has contributed heavily to genomic sequencing efforts and continues to be an important center in this field. Find the latest research from MGI here.

© 2020 Meta ULC. All rights reserved

Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity

bioRxiv

Jul 3, 2014

C T WatsonF Breden

PMID: 990006866

DOI: 10.1101/006866

Abstract

Germline variation at immunoglobulin gene (IG) loci is critical for pathogen-mediated immunity, but establishing complete reference sequences in these regions is problematic because of segmental duplications and somatically rearranged source DNA. We sequenced BAC clones from the essenti...read more

Mentioned in this Paper

SLC3A2 gene
LECT1 gene
Hydatidiform Mole
Immunoglobulin G
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Proximal
Distal
Clone
Sequencing
8
1

Related Papers

Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/sequencing-of-the-human-ig-light-chain-loci-from/990006866