May 13, 2015

Sequencing ultra-long DNA molecules with the Oxford Nanopore MinION

BioRxiv : the Preprint Server for Biology
John M UrbanSusan A Gerbi

Abstract

Oxford Nanopore Technologies’ nanopore sequencing device, the MinION, holds the promise of sequencing ultra-long DNA fragments >100kb. An obstacle to realizing this promise is delivering ultra-long DNA molecules to the nanopores. We present our progress in developing cost-effective ways to overcome this obstacle and our resulting MinION data, including multiple reads >100kb.

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Mentioned in this Paper

Antigens, Tumor-Associated, Carbohydrate
Sequencing
Sequence Determinations, DNA
probe gene fragment
DNA

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