Sequential events in the formation of collagen secretion granules with special reference to the development of segment-long-spacing-like aggregates

The Anatomical Record
M I Cho, P R Garant

Abstract

The formation and maturation of collagen secretion granules in periodontal ligament (PDL) fibroblasts of young male Balb-C mice were studied by electron microscopy and cytochemistry. The Golgi apparatus was composed of several dictyosomes, each consisting of a stack of five smooth-walled cisternae. Each cisterna was connected at both ends to a dilated saccule. The cisternae, with their associated pairs of saccules, underwent progressive maturational changes from the immature to mature face of each dictyosome. The most immature saccules (type 1) were large, spherical, and filled with loosely arranged short filamentous structures. These saccules were continuous with the first and second Golgi cisternae (counting from the immature side). Golgi saccules type 2 were ellipsoidal, associated with the third and fourth cisternae, and contained parallel, elongate filaments. The most mature saccules, type 3, were more rectangular and connected by a short fifth cisterna. They contained aggregated filamentous material in the form of eight segment-long-spacing (SLS)-like crystallites, one in the center and seven at the periphery, to form a basic secretory unit. As type 3 saccules matured, the interconnecting cisterna progressively shortened ...Continue Reading

References

Jan 1, 1975·Cell and Tissue Research·J P Scherft, J N Heersche
Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R R BrunsJ Gross
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·B M Pearse
Jul 1, 1967·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A Rambourg
Jan 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·L D KohnC M Lapiére
Sep 1, 1971·The Journal of Cell Biology·R L Trelstad, A J Coulombre
Aug 5, 1974·Biochemical and Biophysical Research Communications·R HarwoodD S Jackson
May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·B R Olsen, D J Prockop
Dec 19, 1973·Biochemical and Biophysical Research Communications·R HarwoodD S Jackson
Jul 1, 1967·Journal of Ultrastructure Research·E H Leduc, W Bernhard
Oct 8, 1963·Zeitschrift für Zellforschung und mikroskopische Anatomie·J P REVEL, E D HAY

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Citations

May 1, 1992·Calcified Tissue International·M I ChoP R Ramakrishnan
Sep 30, 1988·Clinica Chimica Acta; International Journal of Clinical Chemistry·M M MansourL A Salah
Jun 5, 1987·Journal of Molecular Biology·A P Mould, D J Hulmes
Feb 5, 1990·Journal of Molecular Biology·A P MouldJ A Chapman
Feb 2, 2013·Tissue Engineering. Part a·Amit YaariOded Shoseyov
Feb 1, 1997·Periodontology 2000·D D Bosshardt, K A Selvig
Aug 28, 2015·Proceedings of the National Academy of Sciences of the United States of America·Benjamin D EngelWolfgang Baumeister
Jun 6, 2007·Traffic·Vytaute Starkuviene, Rainer Pepperkok
Jan 1, 1982·Journal of Periodontal Research·P R GarantM R Cullen
May 1, 1983·Journal of Periodontal Research·M I Cho, P R Garant
Jun 1, 1996·The Anatomical Record·D D Bosshardt, H E Schroeder
Sep 1, 1982·The American Journal of Anatomy·G M Wright, J H Youson
Feb 1, 1984·The Anatomical Record·M I Cho, P R Garant
May 1, 1987·The Anatomical Record·M I Cho, P R Garant
Apr 1, 1984·The American Journal of Anatomy·G M WrightD L Babineau
Mar 1, 1995·The Anatomical Record·J M Icardo, E Colvee
Jan 1, 1986·Journal of Periodontal Research·M I Cho, P R Garant

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