Sequential organ failure assessment score and comorbidity: valuable prognostic indicators in chronically critically ill patients

Anaesthesia and Intensive Care
K LeeY Koh

Abstract

Chronically critically ill patients are defined as those who survive initial life-threatening, possibly reversible organ failure(s) but are unable to recover rapidly to a point at which they are fully independent of life support. Accordingly, these patients require mechanical ventilation and medical resources for a long time in an intensive care unit (ICU). The present study analysed demographic, clinical and survival data of chronically critically ill patients, to identify condition(s) related to poor prognosis. A total of 141 chronically critically ill patients were studied retrospectively over a two-year period (July 1, 2003 to June 30, 2005). Their mean lengths of stay in the ICU and in the hospital were 42.9+/-36.4 and 83.9+/-100.5 days respectively. ICU and six-month cumulative mortality rates were 42.6% and 75.9% respectively. Non-survivors had a significantly higher Sequential Organ Failure Assessment (SOFA) score than survivors on day 21 of ICU admission, as well as having significantly lower changes of SOFA scores between days three and 21. Multivariate analysis demonstrated that the SOFA score on day 21 and the Charlson Comorbidity Index were the best predictor of survival for six months after hospital discharge. The...Continue Reading

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Citations

Nov 21, 2012·Tuberculosis and Respiratory Diseases·Mi Hyun KimSoon Kew Park
Jul 28, 2012·American Journal of Respiratory and Critical Care Medicine·Nazir I Lone, Timothy S Walsh
Nov 20, 2014·Critical Care : the Official Journal of the Critical Care Forum·Jonathan A SilversidesNeill Adhikari
Apr 8, 2010·Anaesthesia and Intensive Care·S A Namendys-SilvaA Herrera-Gómez
Apr 10, 2009·The American Journal of Hospice & Palliative Care·Silvio A Namendys-SilvaAngel Herrera-Gómez
Nov 23, 2013·Current Opinion in Anaesthesiology·Inderveer MahalHilary P Grocott

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