Serial endosymbiosis or singular event at the origin of eukaryotes?

Journal of Theoretical Biology
Nick Lane

Abstract

'On the Origin of Mitosing Cells' heralded a new way of seeing cellular evolution, with symbiosis at its heart. Lynn Margulis (then Sagan) marshalled an impressive array of evidence for endosymbiosis, from cell biology to atmospheric chemistry and Earth history. Despite her emphasis on symbiosis, she saw plenty of evidence for gradualism in eukaryotic evolution, with multiple origins of mitosis and sex, repeated acquisitions of plastids, and putative evolutionary intermediates throughout the microbial world. Later on, Margulis maintained her view of multiple endosymbioses giving rise to other organelles such as hydrogenosomes, in keeping with the polyphyletic assumptions of the serial endosymbiosis theory. She stood at the threshold of the phylogenetic era, and anticipated its potential. Yet while predicting that the nucleotide sequences of genes would enable a detailed reconstruction of eukaryotic evolution, Margulis did not, and could not, imagine the radically different story that would eventually emerge from comparative genomics. The last eukaryotic common ancestor now seems to have been essentially a modern eukaryotic cell that had already evolved mitosis, meiotic sex, organelles and endomembrane systems. The long search f...Continue Reading

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Citations

Mar 8, 2019·International Journal of Food Sciences and Nutrition·E Salvucci
Jul 23, 2019·Photobiomodulation, Photomedicine, and Laser Surgery·Mark CronshawPraveen Arany
Feb 23, 2020·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Dave Speijer
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Apr 26, 2021·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Chrystian Rodriguez-ArmentaAdriana Muhlia-Almazan
Jul 14, 2021·The New Phytologist·Elina Welchen, Daniel H Gonzalez

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