Serial Evaluation of Haemostasis Following Acute Trauma Using Rotational Thromboelastometry in Dogs.

Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T
Yaiza HerreroNadja E Sigrist

Abstract

 The aim of this study was to describe the coagulation status of traumatized dogs over the first 24 hours after admission.  In 33 dogs presenting within 6 hours after trauma blood was sampled for rotational thromboelastometry (ROTEM), thrombocyte number and venous blood gas analysis at presentation and 6 and 24 hours thereafter. At each time point, dogs were defined as hypo-, normo- or hypercoagulable based on extrinsic, intrinsic and fibrinogen ROTEM profiles.  Significantly more dogs (11/33) presented hypocoagulable compared with 6 hours (p = 0.046) and 24 hours (p = 0.008) thereafter and none presented hypercoagulable. Significantly more dogs were hypercoagulable (6/23, p = 0.014) and no dog was hypocoagulable at 24 hours compared with presentation. All evaluated ROTEM parameters except maximum lysis were significantly more hypocoagulable at presentation compared with 24 hours thereafter.  Hypocoagulability is more common in acutely traumatized dogs than previously described. Dogs were hypo- or normocoagulable at presentation and the coagulation status changed to normo- or hypercoagulability over the first 24 hours. Clotting times, clot formation and clot firmness but not clot lysis were significantly altered at presentation...Continue Reading

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Citations

Jul 17, 2021·Transfusion·Thomas H EdwardsAnthony E Pusateri

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