PMID: 3383623Jul 1, 1988Paper

Serial pulmonary function testing in patients with systemic lupus erythematosus

Chest
P Q EichackerA Grayzel

Abstract

Previous studies have documented the pulmonary function abnormalities associated with systemic lupus erythematosus (SLE). There are very few data, however, regarding the progression of such changes. To study this question, we evaluated the pulmonary function of a group of 25 patients with SLE from two to seven years after a set of pulmonary function tests had been performed as part of their overall initial assessment. Reductions in diffusing capacity, FVC, and total lung capacity did not change significantly for the group over the period of our study. The mean FEF25-75%, which was initially low, and the mean FEV1/FVC ratio, which was initially normal, both decreased significantly. The observed abnormalities in airway function were not related to smoking history. Other aspects of lupus activity, as measured by serum creatinine levels and clinical activity, did not appear related to progression of lung disease.

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Citations

Jan 20, 2004·Medical Hypotheses·Vinod Kumar Gupta
Oct 14, 2003·American Journal of Respiratory and Critical Care Medicine·Ronald L GibsonBonnie W Ramsey
Mar 19, 2002·Respirology : Official Journal of the Asian Pacific Society of Respirology·Masaaki NakanoFumitake Gejyo
Jan 12, 2008·Chest·Jeffrey J SwigrisKevin K Brown
Oct 23, 2010·Revue des maladies respiratoires·D CarmierE Diot
Dec 25, 2008·Revue des maladies respiratoires·D CarmierE Diot
Apr 4, 2015·Rheumatic Diseases Clinics of North America·Isabel C Mira-Avendano, Andy Abril
Nov 30, 2014·Indian Pediatrics·Md Mahboob AlamRakesh Mondal
Feb 1, 1994·Rheumatic Diseases Clinics of North America·P H White
Aug 1, 1996·The Pediatric Infectious Disease Journal·N HøibyC Koch
Jan 26, 1999·Clinics in Chest Medicine·S MurinR A Matthay
Feb 1, 1993·Baillière's Clinical Rheumatology·D Mulherin, B Bresnihan

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