Series of paraneoplastic vasculitic neuropathy: a rare, potentially treatable neuropathy

Neurology India
Meena A KannanRupam Borgohain

Abstract

Paraneoplastic vasculitic neuropathy (PVN) is a rare paraneoplastic syndrome. It is characterized by non-systemic subacute vasculitic neuropathy. It is most commonly associated with small cell lung cancers (SCLC) and lymphomas. PVN presents as a painful symmetrical or asymmetrical sensorimotor axonal neuropathy. The neurological symptoms may predate the tumor and may be the initial manifestations, or they may develop after a tumor is diagnosed. Recognition of this entity is important because of its potential treatability. To study the clinical features of PVN and briefly review the literature. The data was collected retrospectively from the medical records of our hospital. Of the 14 cases of paraneoplastic neuropathies, 4 had a PVN. The age of onset was more than 50 years and there was no sex preponderance. Pain was seen in three patients. Two patients were previously treated for a thymoma. Two patients, following their presentation with PVN, were diagnosed with a colonic carcinoma and lung carcinoma, respectively. The recognition of PVN is important as this syndrome may respond to immunosuppression and tumor removal.

References

Sep 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·D VincentP Castaigne
Jan 1, 1994·Neurology·D S YoungerA P Hays
Mar 7, 1998·Neurologic Clinics·S J Oh
Jun 17, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·J C AntoineD Michel
Apr 16, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·N E Anderson, P A Barber
Mar 10, 2010·Archives of Neurology·Bruno GiomettoUNKNOWN PNS Euronetwork

❮ Previous
Next ❯

Citations

Sep 7, 2017·Current Opinion in Hematology·Rajat KumarBiju George
Feb 10, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Sandesh GuleriaSurjit Singh
Jul 3, 2017·Pain and Therapy·Panagiotis ZisMarios Hadjivassiliou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurología : publicación oficial de la Sociedad Española de Neurología
J Pascual Calvet
Revista de neurologia
A González-HernándezF Cabrera-Naranjo
© 2022 Meta ULC. All rights reserved