Serious adverse side effects after pupillary dilation in preterm infants

Journal français d'ophtalmologie
A-L LuxE Denion

Abstract

This study aimed at investigating serious side effects of the pupillary dilation protocol used in Caen University Hospital for the screening of retinopathy of prematurity. This protocol includes one drop of phenylephrine 5% and two drops of tropicamide 0.5% instilled at a 5-minute interval. This retrospective study included all premature infants with a birth weight less than or equal to 1500 g and/or a gestational age less than or equal to 30 gestational weeks, hospitalized in the neonatal intensive care unit of Caen University Medical Center, having ocular fundus examinations for retinopathy of prematurity screening between 2009 and 2014. The medical records of patients who died or developed necrotizing enterocolitis were reviewed to analyze the imputability of the two eye drops used for pupil dilation. Five-hundred and twelve infants were included, corresponding to 1033 ocular fundus examinations. No case of death could be ascribed to the use of eye drops. Two cases of necrotizing enterocolitis could be ascribed to the use of tropicamide with a doubtful and plausible intrinsic imputability according to French imputability criteria. The pupillary dilation protocol used in Caen University Hospital for screening of retinopathy o...Continue Reading

References

Apr 1, 1985·American Journal of Diseases of Children·M C Hermansen, L S Sullivan
Mar 1, 1973·The Journal of Pediatrics·C R BauerL Stern
Nov 1, 1970·American Journal of Ophthalmology·N J HaddadF C Riley
Mar 1, 1984·Ophthalmology·S IsenbergE Parelhoff
Jan 1, 1994·Journal of Ocular Pharmacology·M L VuoriK M Saari
Jun 1, 1993·The British Journal of Ophthalmology·S WheatcroftJ McAllister
Mar 15, 1993·American Journal of Ophthalmology·J T WhitsonR D Schoenwald
May 1, 1996·The British Journal of Ophthalmology·D E LawsD Clark
Jun 21, 2005·La Presse médicale·Marc LabetoulleClaire Le Jeunne
Jan 29, 2011·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M Baron-JanaillacP Andrini
Dec 28, 2012·The New England Journal of Medicine·M Elizabeth Hartnett, John S Penn
Jan 2, 2013·Pediatrics·Walter M FiersonUNKNOWN American Association of Certified Orthoptists
Apr 18, 2014·Journal of Clinical Neonatology·Troy A MarkelBrenda B Poindexter

❮ Previous
Next ❯

Citations

Aug 20, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Sejal LahotiC Armitage Harper
Nov 28, 2018·Neonatology·Dominique Bremond-GignacUNKNOWN on behalf of the CLAIR FO Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.