Serious Complications from Staphylococcal aureus in Atopic Dermatitis

Pediatric Dermatology
Devika Patel, Marla N Jahnke

Abstract

Colonization with Staphylococcal aureus is markedly more frequent in individuals with atopic dermatitis (AD) than in unaffected individuals. Chronic scratching leads to worsening of an existing defect in the epidermal barrier, which can allow S. aureus invasion into the bloodstream and subsequent systemic infections. We report two unusual cases of systemic illness in individuals with AD. One developed infective endocarditis followed by a stroke and the other developed septic arthritis and osteomyelitis. We performed an extensive literature review of reported systemic complications caused by S. aureus in patients with AD. Although reports are rare, practitioners should be aware of these important, albeit unlikely, complications of staphylococcal superinfections in individuals with AD.

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Citations

Feb 20, 2008·Immunology and Allergy Clinics of North America·Leonard Bielory
Oct 25, 2016·The Journal of Investigative Dermatology·Patrick M BrunnerUNKNOWN Councilors of the International Eczema Council
Feb 18, 2017·Current Opinion in Infectious Diseases·Willem J B van Wamel
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Mar 23, 2018·International Heart Journal·Shigeaki AoyagiHiroshi Yasunaga
Jul 4, 2018·The British Journal of Dermatology·T TsakokC Flohr
May 16, 2019·The Journal of Dermatology·Yosuke FurumuraKazuyoshi Fukai
Oct 18, 2020·International Journal of Molecular Sciences·Hai Le Thanh NguyenFrançois Niyonsaba
Aug 5, 2020·Journal of the American Academy of Dermatology·Catherine DroitcourtJacob P Thyssen
Jan 29, 2021·Frontiers in Microbiology·Patrycja OgonowskaJoanna Nakonieczna
Feb 1, 2019·Annals of Dermatology·Bok Won ParkKwang Joong Kim

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