PMID: 9441570Jan 24, 1998Paper

Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States

Annals of Internal Medicine
I R WillnerB Waters

Abstract

Memphis and Shelby County, Tennessee, experienced an epidemic of hepatitis A in 1994 and 1995. More than 1700 cases were reported. To characterize the clinical features of patients hospitalized during a large urban epidemic of hepatitis A. Retrospective chart review. 15 acute care hospitals in Shelby County, Tennessee. 256 patients hospitalized with acute hepatitis A. Laboratory findings (such as prothrombin time and bilirubin level), complications, and mortality. The median patient age was 26 years. Thirty-nine complications occurred in 35 patients. Twenty patients (8%) had extrahepatic complications, and 5 (2%) died. Patients 40 years of age and older were more likely to have serious complications, including death (P = 0.014). Sixty-seven patients (26%) presented with coagulopathy (prothrombin time > or = 3 seconds prolonged). Fifty-four patients (21%) had a bilirubin level greater than 170 micromol/L (10 mg/dL). During this epidemic, hepatitis A caused serious illness and death. Complications were more frequent in patients 40 years of age and older, but young, healthy persons were also at risk for severe complications.

Citations

Oct 12, 2002·Journal of Medical Virology·P A BovierC Herzog
Jul 27, 2007·Journal of Gastroenterology·Keiichi FujiwaraMasao Omata
Oct 29, 2013·Best Practice & Research. Clinical Gastroenterology·Tony Whitehouse, Julia Wendon
Jun 27, 2003·Primary Care·Luis S Marsano
Jun 10, 1998·Lancet·R S Koff
Jul 4, 2001·Gastroenterology Clinics of North America·A Regev, E R Schiff
Dec 11, 2002·Journal of Gastroenterology and Hepatology·S K AcharyaS Dattagupta
Jun 10, 2000·Journal of Gastroenterology and Hepatology·G Ostapowicz, W M Lee
Feb 24, 2001·Journal of Gastroenterology and Hepatology·A SegevY A Mekori
Feb 27, 2003·Journal of Paediatrics and Child Health·C R MacIntyreP B McIntyre
Feb 25, 1999·The New England Journal of Medicine·R S Koff
Jan 30, 2004·The New England Journal of Medicine·Allen S Craig, William Schaffner
May 3, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Evangelista SagnelliPietro Filippini
Oct 7, 2006·Current Opinion in Gastroenterology·A Regev, E R Schiff
Oct 7, 2006·Current Opinion in Gastroenterology·R J Fontana
Dec 12, 2001·Journal of Pediatric Gastroenterology and Nutrition·P F Whitington, E M Alonso
Jul 6, 2000·The Pediatric Infectious Disease Journal·G TesovicD Bozinović
Dec 6, 2001·The Pediatric Infectious Disease Journal·D ErtemE Pehlivanoglu
Jul 7, 2005·The Pediatric Infectious Disease Journal·Sebahat CamEnder Pehlivanoglu
Aug 21, 2004·Journal of Clinical Gastroenterology·Vladimir BoginThomas Shaw-Stiffel
Jan 2, 2007·Journal of Clinical Gastroenterology·Manuel Jimenez-SaenzJuan M Herrerias-Gutierrez
May 9, 2006·Journal of Gastroenterology and Hepatology·Zahid HussainPremashis Kar
May 27, 2006·Journal of Gastroenterology and Hepatology·Juan A del OlmoJosé M Rodrigo
Jan 9, 2001·Clinical Microbiology Reviews·J A Cuthbert
Aug 16, 2002·Sexually Transmitted Infections·M G Brook
May 26, 2012·Acta Haematologica·Young Kyung YoonMyung Hyun Nam
Mar 6, 2010·World Journal of Gastroenterology : WJG·Hee Won MoonChang Hong Lee
Jan 1, 2014·World Journal of Gastroenterology : WJG·Kazuto Tajiri, Yukihiro Shimizu
Aug 21, 2012·The Australasian Medical Journal·Vinoth Ponnurangam NagarajanJulius Xavier Scott
Aug 2, 2013·Indian Journal of Pediatrics·K Jagadish KumarS Mamatha
May 14, 2014·Travel Medicine and Infectious Disease·Helena H Askling, Virgil A S H Dalm
Aug 23, 2012·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Jeannette Y Wick
Oct 9, 2014·Case Reports in Gastrointestinal Medicine·Geetika BhattCharlene K Mitchell
Dec 3, 2014·Obstetrics and Gynecology Clinics of North America·Martha W F Rac, Jeanne S Sheffield
Sep 10, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Heng ChiRobert J de Knegt
Feb 18, 2010·Lancet·Deepak JoshiMichael A Heneghan
Apr 28, 2005·American Journal of Public Health·Matthew E Wise, Frank Sorvillo
Oct 11, 2008·Expert Review of Vaccines·Patrick A Bovier
Jul 11, 2008·Expert Opinion on Biological Therapy·Patrick A Bovier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Pediatric Gastroenterology and Nutrition
Surender K YachhaUttam Singh
Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
C RizzoCentral Task Force on Hepatitis A
Journal of Clinical Ultrasound : JCU
Ki Tae SukSoon Ho Um
© 2021 Meta ULC. All rights reserved