Sero-prevalence of Taenia spp. cysticercosis in rural and urban smallholder pig production settings in Uganda

Acta Tropica
Joseph M KunguDelia Grace

Abstract

The pork tapeworm, Taenia solium, is prevalent in Uganda although the prevalence has not been determined in all areas of the country. A cross-sectional study, to determine the sero-prevalence of the parasite in pigs kept under rural and urban production settings, was carried out in three Ugandan districts, Masaka, Mukono and Kamuli. Serum samples from 1185 pigs were tested for the presence of T. solium cysticercosis antigen using the HP10 antigen-ELISA (Ag-ELISA) and the ApDia Ag-ELISA assays. Using parallel interpretation of the two tests showed lower levels of observed prevalence of T. solium in rural production settings (10.8%) compared to urban (17.1%). Additionally, Maximum Likelihood Estimation for evaluating assays in the absence of a gold standard, using TAGS on the R platform, estimated the true sero-prevalence to be lower in rural production setting, 0.0% [0.0-3.2%; 95% confidence interval (CI)] than in urban production setting, 12.3% (4.2-77.5% CI). When the sensitivity/specificity (Se/Sp) of the assays were estimated, assuming conditional independence of the tests, HP10 Ag-ELISA was more sensitive and specific [(Se=53.9%; 10.1-100% CI), (Sp=97.0%; 95.9-100% CI)] than the ApDia assay [(Se=20.2%; 1.5-47.7% CI), (Sp=92...Continue Reading

References

Feb 1, 2002·Preventive Veterinary Medicine·Régis PouillotIan A Gardner
Jul 10, 2004·Tropical Animal Health and Production·H A NgowiA L Willingham
Sep 26, 2009·Tropical Animal Health and Production·Maria M Cortez AlcobedesR Michael E Parkhouse
Feb 4, 2010·PLoS Neglected Tropical Diseases·Alberto PondjaMaria Vang Johansen
Mar 26, 2010·Journal of Helminthology·E AssanaS Geerts
Oct 29, 2010·Journal of Parasitology Research·Arss SeckaStanny Geerts
Apr 6, 2012·PLoS Neglected Tropical Diseases·Kabemba E MwapeSarah Gabriël
Dec 12, 2012·BMC Veterinary Research·Eric E EshiteraNdichu Maingi
Oct 8, 2014·BMC Veterinary Research·Zachary NsadhaCharles Waiswa
Jul 27, 2015·Tropical Animal Health and Production·Uffe Christian BraaeMaria Vang Johansen
Dec 15, 2015·Transboundary and Emerging Diseases·M M DioneD Pezo
Apr 2, 2016·PLoS Neglected Tropical Diseases·Ian W PrayUNKNOWN Cysticercosis Working Group in Peru

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Citations

Mar 22, 2021·Infectious Diseases of Poverty·Zachary NsadhaMarshall W Lightowlers
May 8, 2021·Frontiers in Veterinary Science·Lucrecia Acosta SotoFernando Jorge Bornay-Llinares
Dec 4, 2021·Tropical Medicine & International Health : TM & IH·Fabian DupontBrecht Devleesschauwer

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