Seroepidemiological Investigation of Crimean-Congo Hemorrhagic Fever Virus in Sheep and Camels of Inner Mongolia of China.

Vector Borne and Zoonotic Diseases
Yong LiChangchun Tu

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a highly lethal infectious disease in humans caused by tick-borne Crimean-Congo hemorrhagic fever virus (CCHFV). To determine the potential risk of CCHF in the pastoral area of Northwestern China, the presence of antibody to CCHFV in the sera of two most common tick hosts, sheep and camels, in Inner Mongolia of China was evaluated. The purified recombinant nucleocapsid protein (NP) of CCHFV was prepared from a prokaryotic vector expressing the NP encoding gene, which was employed as the antigen to probe antibody against CCHFV in tick vectors using an immunoblotting assay. In total, 58.3% (35/60) and 54% (12/22) of camels were positive of antibody to CCHFV in sera at Alxa Youqi County and Ulan Hudu Gacha Village of Inner Mongolia Province, respectively. However, only 6.7% (2/30) of sera of sheep were determined positive in antibody to CCHFV in the Wulan Hudug check area in this study. Consequently, these results indicate that 54-58.3% camels were infected by CCHFV after exposure to tick bites in Inner Mongolia, which was significantly higher than 6.7% of infection in the sheep in this area, suggesting there is a certain relationship between the serological reactivity and exposure time to...Continue Reading

References

Oct 1, 1986·The Journal of Hygiene·R SwanepoelB J Barnard
Jan 1, 1982·The American Journal of Tropical Medicine and Hygiene·M A DonetsE A Tkachenko
May 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·O M el-Azazy, E M Scrimgeour
Dec 10, 1997·The American Journal of Tropical Medicine and Hygiene·A S KhanT G Ksiazek
Apr 4, 2000·Tropical Medicine & International Health : TM & IH·R J WilliamsT G Ksiazek
Apr 15, 2003·The Journal of General Virology·Lyudmila YashinaVladimir Petrov
Jan 8, 2009·Pediatric Neurosurgery·Alok M ChaudhariScott W Elton
Jun 26, 2009·Journal of Clinical Microbiology·Surong SunYujiang Zhang
Jul 21, 2011·Asian Pacific Journal of Tropical Medicine·Salim Abadi YaserGhiasi Seyed Mojtaba
Jan 6, 2012·Vector Borne and Zoonotic Diseases·Lisa J JamesonJolyon M Medlock
Jan 21, 2012·Emerging Infectious Diseases·Agustín Estrada-PeñaJosé A Oteo
Mar 30, 2012·Tropical Animal Health and Production·Harun AlbayrakMitat Kurt
Sep 1, 2012·Chinese Journal of Integrative Medicine·Gustav J DobosKyung-Eun Choi
Feb 21, 2013·Vector Borne and Zoonotic Diseases·Viktória NémethFerenc Jakab
May 7, 2013·BMC Infectious Diseases·Muhammad Masroor AlamSyed Sohail Zahoor Zaidi
Jun 24, 2014·Ticks and Tick-borne Diseases·Anna PapaSmaragda Sotiraki
Sep 26, 2014·PLoS Neglected Tropical Diseases·Kurtesh SherifiAndreas Krüger
Jul 5, 2015·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jane P MessinaSimon I Hay
Jul 29, 2016·Vector Borne and Zoonotic Diseases·Marc MertensMartin H Groschup
Jun 13, 2017·Vector Borne and Zoonotic Diseases·Miriam A SasMartin H Groschup
Aug 5, 2017·Virology Journal·Hajer M SulimanImadeldin E Aradaib
Feb 1, 2018·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Stephen BalinandiTrevor R Shoemaker
Feb 8, 2018·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·A N Lukashev, A A Deviatkin
Jun 19, 2018·Emerging Infectious Diseases·Sabeehah VawdaFelicity Burt
Nov 21, 2018·Emerging Infectious Diseases·Matthew A VoorheesRandal J Schoepp

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
electrophoresis
column affinity chromatography
enzyme-linked immunosorbent assay
antibody assay
ELISA

Software Mentioned

BLAST

Related Concepts

Related Feeds

Argentine Hemorrhagic Fever

Argentine hemorrhagic fever (AHF) is an endemo-epidemic disease caused by junín virus (JUNV), a member of the arenaviridae family. Discover the latest research on AHF here.