Abstract
Helicobacter pylori (H. pylori) infection has been linked to gastritis, diarrhea, peptic ulcers, failure-to-thrive, anemia, as well as predisposition to gastric malignancies. Because many internationally adopted children have diarrhea, failure-to-thrive, and anemia on arrival to the US, we determined the prevalence of HP antibodies among these children. Serum samples from 226 unselected children from 18 countries who were evaluated in the International Adoption Clinic at New England Medical Center were tested for antibodies to H. pylori. The results of serologic screening were analyzed in relation to age at adoption, site of residence prior to adoption, weight and height, and the presence or absence of anemia, diarrhea, or intestinal parasites. 31% of internationally adopted children had antibodies to H. pylori. The presence of H. pylori-antibodies was associated with residence in an orphanage (vs. foster care) prior to adoption, older age at adoption, and coinfection with intestinal parasites. No direct effects on height or weight were identified; no associations with diarrhea or anemia were found. Internationally adopted children have a high incidence of exposure to H. pylori, as diagnosed serologically. Residence in an orpha...Continue Reading
References
Dec 1, 1992·Journal of Clinical Microbiology·N J TalleyA R Zinsmeister
Nov 1, 1992·Journal of Clinical Pathology·C DoglioniG Viale
Jun 22, 1991·Lancet·P D KleinE O Smith
Dec 1, 1990·Journal of Clinical Microbiology·J E ThomasM A Kehoe
Feb 1, 1990·Archives of Disease in Childhood·P B SullivanB M Greenwood
Jul 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·L T Weaver
Oct 12, 1995·The New England Journal of Medicine·J H Walsh, W L Peterson
Oct 29, 1994·BMJ : British Medical Journal·P PatelD P Strachan
Feb 1, 1994·Journal of Clinical Microbiology·J RaymondC Dupont
Jan 1, 1996·Scandinavian Journal of Infectious Diseases·P LindkvistJ Giesecke
Dec 1, 1996·The Pediatric Infectious Disease Journal·J ClemensA Banik
Jan 1, 1997·Scandinavian Journal of Gastroenterology·G OberhuberM Stolte
Jul 1, 1997·Archives of Disease in Childhood·F PerriA Andriulli
Nov 14, 1997·Developmental Medicine and Child Neurology·P J LewindonP B Sullivan
Nov 14, 1997·Journal of Pediatric Gastroenterology and Nutrition·K J GoodmanT Collazos
Dec 6, 1997·Archives of Disease in Childhood·C H FallS Duggleby
Apr 29, 1998·Journal of Pediatric Gastroenterology and Nutrition·A DaleL T Weaver
Aug 26, 1998·BMJ : British Medical Journal·G OderdaG Bona
Feb 5, 1999·Journal of Pediatric Gastroenterology and Nutrition·S J Czinn
Aug 3, 1999·Pediatrics·P S Ganga-ZandzouF Gottrand
Aug 3, 1999·Pediatrics·S KatoK Iinuma
Sep 25, 1999·The American Journal of Tropical Medicine and Hygiene·J M QuiñonezR E Bégué
Nov 24, 1999·The New England Journal of Medicine·L C Miller
Jan 12, 2000·Journal of Pediatric Gastroenterology and Nutrition·A KindermannS Koletzko
Jan 29, 2000·Archives of Disease in Childhood·Y H ChoeY C Hong
Mar 4, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·J A Castro-RodríguezM Penny
Mar 4, 2000·Journal of Pediatric Gastroenterology and Nutrition·B DrummG Oderda
Jun 6, 2000·The Journal of Pediatrics·B D Gold, K Goodman
Jun 8, 2001·Journal of Pediatric Endocrinology & Metabolism : JPEM·A BüyükgebizB Büyükgebiz
Jul 11, 2001·The Journal of Pediatrics·Y H ChoeY C Hong
Sep 15, 2001·The New England Journal of Medicine·J G Fox, T C Wang
Nov 6, 2001·Pediatrics·D J PassaroJ Parsonnet
Nov 8, 2001·Journal of Pediatric Gastroenterology and Nutrition·T RichterW Kiess
Nov 20, 2001·The Journal of Pediatrics·N L Jones, P M Sherman
Nov 20, 2001·The Journal of Pediatrics·C ImrieB Drumm
May 28, 2002·Scandinavian Journal of Infectious Diseases·Kaija-Leena KolhoHilpi Rautelin
Citations
Mar 11, 2005·The Journal of Pediatrics·Steven J Czinn
Jul 16, 2005·Clinical Microbiology Reviews·Thomas S MurrayMichael Cappello
Jan 19, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Laurie C Miller
Jan 18, 2006·Chinese Journal of Digestive Diseases·Kamal E Bani-HaniBayan K Bani-Hani
Jan 22, 2008·Helicobacter·Rania EgbariaRon Shaoul
Apr 21, 2010·Helicobacter·Sarah CherianDavid Alan Forbes
Jul 18, 2006·Journal of Pediatric Nursing·Teena M McGuinness, Janyce G Dyer
Mar 12, 2011·Physical & Occupational Therapy in Pediatrics·Linda Grey Tirella, Laurie C Miller
Dec 3, 2015·Journal of Pediatric Gastroenterology and Nutrition·Gal Dror, Khitam Muhsen
Jan 18, 2017·Helicobacter·Samantha MoraisBárbara Peleteiro
Oct 11, 2005·Annals of Saudi Medicine·Hassan A Al-Shamahy