PMID: 8954349Nov 1, 1996Paper

Serological characterisation of anti-endotoxin sera directed against the conjugates of oligosaccharide core of Escherichia coli type R1, R2, R3, J5 and Salmonella Ra with tetanus toxoid

FEMS Immunology and Medical Microbiology
C LugowskiS Rowinski

Abstract

The covalent conjugates of oligosaccharide core: Escherichia coli type R1, R2, R3, J5 and Salmonella Ra with tetanus toxoid have been prepared using reaction of reductive amination. The neoglycoconjugates were good immunogens in rabbits yielding a high level of anti-lipopolysaccharide antibodies of IgG class. The antibodies were used to examine the possibility of their reactions with smooth lipopolysaccharides. We have found that all antisera were able to react with the lipopolysaccharide molecules of identical or related core type, possessing core oligosaccharides substituted with O-specific chains. These reactions were shown in both the ELISA assay and the immunoblotting test.

References

Dec 1, 1988·FEMS Microbiology Immunology·A RomanowskaE Romanowska
Mar 1, 1988·The Journal of Infectious Diseases·J L ShenepD F Westenkirchner
Sep 1, 1994·European Journal of Biochemistry·S Müller-LoenniesH Brade
May 1, 1996·European Journal of Biochemistry·T NiedzielaC Lugowski

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Citations

May 26, 1999·Infectious Disease Clinics of North America·A K Bhattacharjee, A S Cross
Aug 27, 2013·Virulence·Alan S Cross
Jul 17, 2010·Acta Ophthalmologica·Marta Misiuk-HojłoStanisław Szymaniec
Jun 3, 2000·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·S J LugowskiJ Semple
Dec 11, 2013·The Journal of Biological Chemistry·Tomasz K GozdziewiczJolanta Lukasiewicz
May 26, 1999·FEMS Immunology and Medical Microbiology·E RomanowskaC Lugowski

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