PMID: 4473427Sep 1, 1974

Serological comparison of five arginine-utilizing Mycoplasma species by two-dimensional immunoelectrophoresis

Infection and Immunity
C E Thirkill, G E Kenny


Five arginine-utilizing, nonglycolytic Mycoplasma species were compared serologically by two dimensional immunoelectrophoresis. The survey included: Mycoplasma hominis, Mycoplasma arthritidis, Mycoplasma gateae, Mycoplasma gallinarum, and three strains of Mycoplasma arginini. Although the M. arginini strains showed strong cross-reactions, each strain produced a different antigenic profile which was distinct and which indicated significant antigenic differences between strains. The M. arginini strains showed strong relationships with M. gateae; lesser cross-reactions were observed with other strains. Common antigens were demonstrable in the entire group. When all these species were compared with a glycolytic species, Mycoplasma gallisepticum, no cross-reactions were observed. Two-dimensional immunoelectrophoresis was a far more sensitive technique than double-immunodiffusion since as many as 20 components could be resolved.

Related Concepts

Antigens, Bacterial
Arginine hydrochloride
Cross Reactions
Immune Sera
Mycoplasma putrefaciens
Chinchilla Rabbits

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The Journal of Immunology : Official Journal of the American Association of Immunologists
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