Serological Detection of Anti-Leptospira Antibodies in Shelter Cats in Malaysia

Topics in Companion Animal Medicine
Abdul Rahman AlashrafR Radzi

Abstract

Leptospirosis is one of the most widespread zoonotic diseases and despite extensive research, there is still a paucity of information regarding this disease in cats. The aim of this study was to investigate the prevalence of leptospirosis among the shelter cat population in Malaysia and to determine the most common infective Leptospira serogroups among them. Blood samples were collected from a total of 110 cats from 4 different shelters. The sampled cats appeared healthy, with minimal evidence of feline upper respiratory disease. The Microscopic Agglutination Test was used to detect anti-Leptospira antibodies against 20 pathogenic serovars. Based on a cut-off antibody titer of ≥1:100, 20 of 110 sheltered cats, showed presence of anti-Leptospira antibodies against at least 1 serovar. The serodetection of leptospirosis was 18.18% (95% confidence interval 12.09-26.42). The most commonly detected serogroups were Bataviae, Javanica, and Ballum, with antibody titers ranging from 1:100 to 1:1600. Knowledge of the predominant infective serovars in hosts worldwide and regionally is imperative for understanding the epidemiology of this zoonotic disease. Serosurveillance is the first step in this process. Further studies are warranted for...Continue Reading

Citations

Mar 4, 2020·International Journal of Environmental Research and Public Health·Andrea MurilloJosep Pastor
Mar 11, 2020·PloS One·Abdul Rahman AlashrafMuhammad Sabri Abdul Rahman
Feb 26, 2020·Journal of Feline Medicine and Surgery·Andrea MurilloJosep Pastor
Jan 23, 2021·International Journal of Environmental Research and Public Health·Lucas N PazMelissa H Pinna
Jul 17, 2021·Topics in Companion Animal Medicine·Soon Heng GohMohd Azri Roslan
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Juin Jia SimMuhammad Waseem Aslam

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