PMID: 3754083Jan 1, 1986Paper

Serological evidence for the role of bacterial infections in the pathogenesis of thyroid diseases

Acta Medica Scandinavica
V V ValtonenP H Mäkelä

Abstract

Subacute thyroiditis is generally believed to be of viral origin, and infection is also suspected of playing a role as a triggering factor in the pathogenesis of autoimmune thyroid diseases. We have measured a broad spectrum of bacterial and viral antibodies in paired sera of 32 patients with thyroid disease of recent onset. The data indicate a preceding infection in 14 (44%) of the patients, enterobacterial in 5, streptococcal in 4 and staphylococcal in 2. A viral infection was suggested in 6 patients, in each case caused by different agents; 3 of them also showed evidence of a bacterial infection. Patients with positive microbial serology were found in all diagnostic groups, including subacute thyroiditis, Graves' disease and Hashimoto's disease. These results suggest an association between a preceding bacterial infection and the development of thyroid disease in some patients.

References

Nov 1, 1977·Acta Endocrinologica·K BechJ H Larsen
Mar 24, 1979·Lancet·J M SáezA Casanova
Aug 1, 1978·Journal of Clinical Microbiology·P Saikku, J Paavonen
Mar 1, 1979·Clinics in Endocrinology and Metabolism·R Volpé
Jan 1, 1979·Journal of Medical Virology·P Väänänen, A Vaheri
Aug 5, 1978·British Medical Journal·M T ReynoldsN S Mair
Dec 1, 1976·Annals of Internal Medicine·L Shenkman, E J Bottone
Jun 1, 1985·Annals of the Rheumatic Diseases·V V ValtonenP H Mäkelä
Dec 28, 1974·Lancet·M Von Bonsdorff, C Friman
Mar 1, 1981·The Journal of Clinical Endocrinology and Metabolism·N OkitaR Volpe
Jan 1, 1980·Metabolism: Clinical and Experimental·A KiddR Volpé
Nov 15, 1958·Lancet·I M ROITT, D DONIACH

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Citations

Dec 13, 2003·Endocrine Reviews·Bellur S PrabhakarTerry J Smith
Jun 24, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·K LuotolaA Pasternack
Mar 20, 2004·Clinical and Experimental Immunology·M J Simmonds, S C L Gough
Jul 14, 2010·Current Opinion in Endocrinology, Diabetes, and Obesity·Kouki Mori, Katsumi Yoshida
May 1, 1989·Journal of Internal Medicine·K J Mattila
Jul 11, 1996·The New England Journal of Medicine·C M Dayan, G H Daniels
Feb 29, 2020·Best Practice & Research. Clinical Endocrinology & Metabolism·Alessandro AntonelliPoupak Fallahi

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