Serological Evidence of Dengue and West Nile Virus Human Infection in Juarez City, Mexico

Vector Borne and Zoonotic Diseases
Pedro M PalermoDouglas M Watts

Abstract

Arboviruses are significant causes of human and animal diseases, globally. In the Rio Grande Valley of the United States-Mexico border region, endemic transmission of Dengue (DENV), Zika (ZIKV), and West Nile (WNV) viruses have been documented as a cause of human disease. Otherwise, very little is known about the distribution of arboviruses and their possible cause of human disease in other areas of the United States-Mexico border region. Therefore, a pilot serosurvey was conducted to determine if there was evidence of DENV and WNV infection among a human cohort in Anapra, Ciudad Juarez, Mexico. Baseline blood samples were obtained from 78 participants during May-June, 2015 and from 60 of the same participants again during November-December, 2015, and all the samples were tested for DENV and WNV indirect immunoglobulin G antibodies by an enzyme-linked immunosorbent assay and plaque reduction neutralization test (PRNT). The results showed that 14.1% (n = 11) of the 78 participants had neutralizing antibody to DENV and 5.13% (n = 4) had WNV-neutralizing antibody. Among 48 of 60 participants who were negative for DENV and WNV antibody during the baseline survey, 10.4% (n = 5) had acquired antibody to DENV (n = 4) and WNV (n = 1) b...Continue Reading

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Citations

Aug 5, 2020·Vector Borne and Zoonotic Diseases·Pedro M PalermoDouglas M Watts
May 5, 2021·Vector Borne and Zoonotic Diseases·Daniel Nunez-AvellanedaBradley J Blitvich

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BETA
ABTS
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