Jan 1, 1977

Serological identification of the new cold agglutinin specificity anti-Gd

Vox Sanguinis
D RoelckeW Ebert

Abstract

The specificity anti-Gd of human cold autoagglutinins is characterized using untreated and enzyme-treated human red blood cells. Gd determinants of human RBC are resistant to proteases, but are inactivated by neuraminidase (RDE). In contrast, I/i determinants are not inactivated by proteases or RDE, while Pr1-3 determinants are inactivated by proteases and RDE, and Pra determinants are resistant to RDE, but are inactivated by proteases.

Mentioned in this Paper

Autoantibodies
Cold Temperature
Antigenic Specificity
Peptide Hydrolases
Neuraminidase
Agglutinins
Sialic Acids
Antibody Specificity
Blood Group Antigens

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