Serological mapping of HLA-epitopes with monoclonal antibodies and its interpretation by sequenced HLA-molecules.

Tissue Antigens
J HarpprechtW Müller-Ruchholtz

Abstract

For the study of the epitope distribution on HLA class I molecules, blocking studies were carried out with a competitive radioimmuno assay using 3H labelled monoclonal antibodies (MAbs) against various HLA epitopes. The results were discussed with the help of known HLA amino acid sequences, and the positions of the following epitopes were suggested: A2/Aw69; A2/28; A2/11/25/26/28/29/30/31/Aw33/34; A25/32; Bw4; B7/Bw22,42; Bw6.

References

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Citations

Jan 4, 1993·Journal of Immunological Methods·B SánchezA Núñez-Roldán
Feb 1, 1991·Human Immunology·N Akkoc, J C Scornik
Aug 26, 2014·Blood Cells, Molecules & Diseases·Maria S Pombo-de-OliveiraAnthony M Ford
Dec 18, 2004·Human Immunology·Steve TakemotoRene J Duquesnoy
Mar 1, 1992·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·M A Jutila

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