PMID: 68765Jan 1, 1977Paper

Serological relationships between rotaviruses from different species as studied by complement fixation and neutralization

Archives of Virology
M E ThoulessJ A Herring

Abstract

Human, piglet, mouse, foal, lamb, calf and rabbit rotaviruses all infected, but could not readily be subcultured in LLC MK2 cells. Cells infected with mouse and calf rotaviruses reacted by indirect immunofluorescence (FA) with convalescent serum from children, piglets, mice, foals, lambs, calves or rabbits, taken after rotavirus infection. Human, calf, piglet, mouse and foal rotaviruses reacted with human, calf, mouse, foal and lamb convalescent serum by complement fixation (CF). It was not possible to distinguish between different rotaviruses by CF or FA. Neutralization tests, however, detected species-specific rotavirus antigens. Any virus was neutralized by a much higher dilution of homologous species convalescent serum than by any heterologous serum. With the exception of the mouse virus there was very little cross reaction. However, in sera with a very high neutralizing titre for the homologous virus the titre was proportionately raised against heterologous virus. It is, therefore, now possible to type to species an unknown rotavirus by a neutralization test in LLC MK2 cells using convalescent serum from each species.

References

Oct 25, 1975·Lancet·J E BanatvalaG N Woode
Jan 1, 1976·The Journal of Infectious Diseases·A Torres-MedinaA Z Kapikian
Dec 18, 1975·Nature·J F NewmanG N Woode
May 1, 1976·The Journal of General Virology·J C Bridger, G N Woode
May 1, 1976·Journal of Medical Microbiology·G N WoodeG Jackson
Oct 16, 1976·The Veterinary Record·A S BrydenT H Flewett
Feb 1, 1977·Journal of Medical Microbiology·A S BrydenT H Flewitt
Nov 1, 1975·Journal of Medical Microbiology·J C BridgerH Davies
Oct 1, 1972·The Journal of General Virology·H J Els, G Lecatsas
Dec 29, 1973·Lancet·T H FlewettH Davies
Dec 1, 1972·Infection and Immunity·D H Much, I Zajac

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Citations

Jan 1, 1984·Archives of Virology·C K OjehA J Herring
Jan 1, 1981·Archives of Virology·J A ShirleyT H Flewett
Jan 1, 1982·Archives of Virology·K SatoM Matumoto
Jan 1, 1978·Archives of Virology·T H Flewett, G N Woode
Jan 1, 1982·Archives of Virology·M E ThoulessT H Flewett
Jan 1, 1979·Archives of Virology·M S McNultyJ B McFerran
Mar 13, 1979·Medical Microbiology and Immunology·L Brade, W A Schmidt
Dec 1, 1981·Veterinary Research Communications·M A ShalabyR M El-Karamany
Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·A C LinharesY B Gabbay
Jan 1, 1988·Comparative Immunology, Microbiology and Infectious Diseases·G CastrucciV Aldrovandi
Jun 1, 1988·Epidemiology and Infection·N MinamotoY Suzuki
Feb 12, 1981·The New England Journal of Medicine·N R Blacklow, G Cukor
Jan 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·H B GreenbergR M Chanock
May 11, 1984·Nucleic Acids Research·M L Dyall-Smith, I H Holmes
Nov 26, 1977·British Medical Journal·M E ThoulessT H Flewett
Jan 1, 1989·Clinical Microbiology Reviews·M L Christensen
Nov 17, 1978·Medical Microbiology and Immunology·J Kurtz, T Lee
Jan 1, 1982·Journal of Medical Virology·B M TotterdellJ E Banatvala
Apr 1, 1980·The Journal of Pediatrics·M C Steinhoff
Aug 4, 2015·Journal of Virological Methods·Peter H OttoMandy C Elschner
Dec 1, 1982·Pediatric Annals·L K PickeringS A Plotkin
Sep 1, 1979·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·P Debouck, M Pensaert
Feb 1, 1980·Acta Pathologica Et Microbiologica Scandinavica. Section C, Immunology·A B Otnaess, I Orstavik
Nov 1, 1977·Journal of Clinical Microbiology·D J Ellens, P W de Leeuw
Feb 1, 1988·Journal of Clinical Microbiology·H S Nagesha, I H Holmes
Aug 1, 1983·Journal of Clinical Microbiology·R G WyattA Z Kapikian
Sep 1, 1983·Journal of Clinical Microbiology·Y HoshinoA Z Kapikian
Mar 1, 1983·Journal of Virology·S SonzaI H Holmes
Aug 1, 1984·Journal of Clinical Microbiology·P A OffitS A Plotkin

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