PMID: 8500487Feb 1, 1993Paper

Serological response to coagulase-negative staphylococci in patients with peritonitis on continuous ambulatory peritoneal dialysis

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
M DrydenI Phillips


Sera and dialysis effluent from 20 patients on continuous ambulatory peritoneal dialysis (CAPD) with coagulase-negative staphylococcal (CNS) peritonitis were examined by immunoblotting for antibody activity against CNS. Immunoblotting was highly sensitive and demonstrated significantly greater antibody activity in serum and dialysate of infected patients compared with that of uninfected CAPD patients or healthy volunteers. Fourteen of 20 infected CAPD patients had strong antibody activity (> 7 bands); one patient had equivocal activity. Five patients had weak antibody activity, two of whom suffered from recurrent peritonitis with distinguishable CNS strains despite a satisfactory CAPD technique. One patient with a poor CAPD technique had strong antibody activity, but suffered from recurrent peritonitis. Examination of sequential sera suggested that seroconversion occurred soon after insertion of the Tenckhoff catheter, possibly in the absence of clinical infection. Antibody activity against a 25 kDa staphylococcal protein was significantly associated with peritonitis.


Aug 1, 1992·Journal of Medical Microbiology·M S DrydenI Phillips
Jun 1, 1991·The Journal of Hospital Infection·H A Ludlam
Jan 1, 1990·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·W C Lye
Dec 1, 1990·Journal of Clinical Microbiology·C C PatrickG S Patrick
Feb 1, 1987·Journal of Clinical Microbiology·E J AitchisonI D Farrell
Aug 1, 1986·Journal of Medical Microbiology·L A Clark, C S Easmon
Aug 1, 1986·Journal of Clinical Pathology·L A Clark, C S Easmon
Sep 1, 1984·Kidney International·J T Dulaney, F E Hatch
Jun 1, 1983·The Journal of Infectious Diseases·H A VerbrughP K Peterson

❮ Previous
Next ❯


Oct 1, 1995·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J S Cameron

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.