Serology as a diagnostic tool for surveillance and control of schistosomiasis in Holambra, São Paulo State, Brazil

Cadernos de saúde pública
Cybele GargioniHermínia Yohko Kanamura

Abstract

The present study aimed to evaluate the incorporation of the immunofluorescence test (IFT) with adult parasite paraffin sections as antigen substrate for the detection of IgM antibodies (IgM-IFT), as a diagnostic method in the schistosomiasis control program in the county (municipality) of Holambra, São Paulo State, Brazil. This city was selected for this study based on its low endemicity for schistosomiasis, the first cases having been reported in 1993, and because of the need to implement a control program with more sensitive diagnostic techniques. 202 individuals underwent IgM-IFT, with 48 serologically positive cases; of these, 28 were tested with the Kato-Katz technique, using three stool samples. Schistosoma mansoni eggs were found in 14 individuals, with egg counts varying from 2.7 to 224 per gram of stool. The results indicate the potential usefulness of IgM-IFT as a screening test, subject to subsequent confirmation using a parasitological method, in low-endemic areas for schistosomiasis.

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Citations

Nov 14, 2012·Memórias do Instituto Oswaldo Cruz·Marta Cristhiany Cunha PinheiroFernando Schemelzer Moraes Bezerra
Aug 30, 2012·Revista Da Sociedade Brasileira De Medicina Tropical·Teiliane Rodrigues CarneiroFernando Schemelzer Moraes Bezerra
Jan 16, 2013·TheScientificWorldJournal·Rafaella Fortini Queiroz GrenfellPaulo Marcos Zech Coelho
Oct 29, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Israel Gomes de Amorim SantosFábio André Brayner

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