PMID: 9163992May 1, 1996Paper

Seropositivity for anti-trypanosoma cruzi antibodies among blood donors of the "Hospital Universitário Regional do Norte do Paraná", Londrina, Brazil

Revista Do Instituto De Medicina Tropical De São Paulo
E M ReicheJ V Jankevicius

Abstract

The most frequent form of acquisition of Chagas' disease in endemic areas was the transmission through the feces of contaminated triatominae. However, special attention should be paid in urban areas to transmission by blood transfusion, justifying the compulsory screening of blood donors. Early investigations at blood banks in the town of Londrina, Brazil, demonstrated that the seroprevalence of anti-Trypanosoma cruzi antibodies among blood donors was approximately 7.0% in the fifties. Further studies demonstrated practically the same seroprevalence until the eighties. In an attempt to obtain data about the real dimension of the seropositivity for anti-Trypanosoma cruzi antibodies in the region, the authors carried out a large-scale study on 45,774 serum samples from blood donors of the Hemocentro of Hospital Univesitário Regional do Norte do Paraná (HURNP), Universidade Estadual de Londrina. The immunological tests were done at the Division of Clinical Immunology of HURNP from May 1990 to December 1994. The serum samples were studied by the indirect hemagglutination assay (IHA, using kits commercially obtained from EBRAM) and by indirect immunofluorescence (IFI, using kits from LIO SERUM) with anti-human IgG conjugate (LABORCL...Continue Reading

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Citations

Sep 28, 2005·Biochemical Genetics·Ester Tartarotti, Carlos Roberto Ceron
Apr 10, 2010·Medical and Veterinary Entomology·E TartarottiC R Ceron
Mar 24, 2006·Revista Do Instituto De Medicina Tropical De São Paulo·Divina Seila de Oliveira-MarquesFrancisco Gregori Junior
Aug 8, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Diego Lopes Paim MirandaMitermayer Galvão Dos Reis
Jun 1, 1999·Revista de saúde pública·A M BonamettiT Matsuo
Dec 17, 1997·Journal of Clinical Microbiology·V M MonteónP A Lopez

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