Seroprevalence and Risk Factors for Hepatitis B Virus Infection in Adolescent Blood Donors within Selected Counties of Western Kenya.

BioMed Research International
Hilary O AwiliGerald M Muchemi

Abstract

Hepatitis B virus is a widespread public health menace approximated to have infected 257 million people chronically by 2015. Data on the prevalence of HBV is important in formulating public health policies on HBV control like safe blood transfusion. Adolescents aged 15 to 24 years, known to engage in risky activities associated with HBV spread, constitute major blood donors in Kenya. Notwithstanding current blood donation safety measures, HBV still remain hazardous transfusion-transmissible infections in donated blood. This study therefore was to determine the prevalence of HBsAg and related risk factors among this donor group. A cross-sectional study was conducted from April 2019 to August 2019 in Siaya, Kisumu, and Homa Bay counties. One thousand (1000) voluntary blood donors 18 to 25 years old were recruited. A predonation questionnaire was used to record their sociodemographic features and prior risk exposures. Blood samples were initially tested for HBsAg using Murex HBsAg Version 3 (DiaSorin, UK) and positives confirmed using ARCHITECT HBsAg Qualitative Confirmatory assay (Abbott Ireland) as per the manufacturer's instructions. A result was considered positive if the first and confirmatory tests were all reactive. General...Continue Reading

References

May 8, 2009·International Journal of Epidemiology·Adela Paez JimenezArnaud Fontanet
Jan 14, 2011·Virology Journal·Ahizechukwu C EkeChukwuanugo Ogbuagu
Apr 11, 2012·World Journal of Hepatology·Elisabetta FrancoLaura Zaratti
Sep 11, 2013·BMC Research Notes·Beatrice Mukami MuriukiSamoel Ashimosi Khamadi
Apr 6, 2017·Tropical Medicine & International Health : TM & IH·Roland GarveChristian G Meyer

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